This paper discusses the need for an adaptive and iterative process for the design of ordinary domestic buildings that meet human needs. The approach described here is to use Pattern Languages as fitness criteria to guide an iterative design optimisation. To complement this, a Form Language for domestic buildings is proposed that is physically buildable, sufficiently flexible, and suitable for ...

In this paper, we consider statistical tests for inter-subject and total variabilities between treatments under crossover designs. Since estimators of variance components for inter-subject variability and total variability in crossover design are not independent, the usual F-test cannot be applied. Alternatively, we propose a test based on the concept of the extension of the modified large samp...

OBJECTIVE. To identify correlates of incident bacterial vaginosis (BV) diagnosed with Nugent scoring among high-risk women. STUDY DESIGN. We conducted both cohort and case-crossover analyses, stratified by HIV infection status, based on 871 HIV-infected and 439 HIV-uninfected participants in the HIV Epidemiology Research Study, conducted in 4 US sites in 1993-2000. RESULTS. BV incidence was 21%...

The case-crossover study design is a popular analytic tool for estimating the effects of triggers of acute outcomes by environmental exposures. Although this approach controls for time-invariant confounders by design, it may allow for selection bias and confounding by time-varying factors. We conducted a simulation study of the sensitivity of the symmetric bidirectional case-crossover design to...

A hardware/software platform for intrinsic evolvable hardware is designed and evaluated for digital circuit design and repair on Xilinx Virtex II Pro Field Programmable Gate Arrays (FPGAs). Dynamic bitstream compilation for mutation and crossover operators is achieved by directly manipulating the bitstream using a layered framework. Experimental results on a case study have shown that benchmark...

The main real-coded genetic algorithm (RCGA) research effort has been spent on developing efficient crossover operators. This study presents a taxonomy for this operator that groups its instances in different categories according to the way they generate the genes of the offspring from the genes of the parents. The empirical study of representative crossovers of all the categories reveals concr...