To evaluate the effect of decreasing dietary protein on growth performance, carcass traits, and intestinal mucosal morphometry, 180 female Hubbard strain broiler chickens were divided into 3 groups and fed 3 isoenergetic diets ad libitum from 14 d of age until slaughter age (49 d). The treatments varied according to 3 protein levels: high-protein diet (HiP, 22.5% CP, DM basis), medium-protein d...

The present study was carried out to determine the effects of the inclusion of a spore-forming probiotic (Bacillus subtilis) in laying Japanese quail diets as an alternative to growth-promoting antibiotics to help produce healthy eggs and meat. This experiment was conducted as a completely randomized design with three treatments (control, 0.05% bacitracin methylene disalicylate (BMD), or 0.1% B...

Background & Aim:  Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical medicine. The adverse effects they produce in the gastrointestinal tract however, often limit their utility. Oxidative stress has been shown to occur in the small intestine in response to the oral administration of indomethacin. In view of this, the effect of thyme essential oil, an agent with anti-o...

The intestinal epithelium undergoes a marked adaptive response following loss of functional small bowel surface area characterized by increased crypt cell proliferation and increased enterocyte migration from crypt to villus tip, resulting in villus hyperplasia and enhanced nutrient absorption. Hedgehog (Hh) signaling plays a critical role in regulating epithelial-mesenchymal interactions durin...

background & aim:  non-steroidal anti-inflammatory drugs (nsaids) are commonly used in clinical medicine. the adverse effects they produce in the gastrointestinal tract however, often limit their utility. oxidative stress has been shown to occur in the small intestine in response to the oral administration of indomethacin. in view of this, the effect of thyme essential oil, an agent with an...

AIM The aim of this study was to evaluate the effect of probiotics on the recovery of the bowel atrophy induced by malnutrition in rats. METHODS Twenty-and-six Wistar rats (200-250g) were fed with either a normoproteic (sham group, n=6) or a free-protein diet (n=20) during 12 days. Twelve malnourished rats were randomized to recover during 15 days with either a hydrolyzed diet (control group,...

Angiotensin converting enzyme (ACE) has been shown to be involved in regulation of apoptosis in nonintestinal tissues. This study examined the role of ACE in the modulation of intestinal adaptation utilizing ACE knockout mice (ACE-/-). A 60% small bowel resection (SBR) was used, since this model results in a significant increase in intestinal epithelial cell (EC) apoptosis as well as proliferat...

This experiment was conducted to investigate dietary putrescine effects on broiler performance. Treatments were 6 levels of putrescine (0, 0.01, 0.02, 0.03, 0.04 & 0.05 %) added to a basal diet and fed to 4-32 day old broilers. The weekly growth performance was recorded, and ileal digesta and small intestine samples were collected at the end of the 2nd and 3rd week of age. At 21 d, body weight ...