نتایج جستجو برای: ctrp 3
تعداد نتایج: 1811344 فیلتر نتایج به سال:
Background: Kidney renal clear cell carcinoma (KIRC) originates from proximal tubular cells and is the most common subtype of carcinoma. KIRC characterized by changes in lipid metabolism, obesity a risk factor for it. C1q And TNF Related 1 (C1QTNF1), novel adipokine member TNF-related protein (CTRP) family, has been shown to affect progression various cancers. However, role C1QTNF1 not studied....
OBJECTIVES Cartonectin is a novel adipokine of the C1q complement/TNF-related protein (CTRP) superfamily, with glucose lowering effects, anti-inflammatory and cardio-protective properties. We sought to investigate circulating cartonectin concentrations in subjects with type 2 diabetes mellitus (T2DM) as well as age and BMI matched control subjects. We also examined the effects of a 2 hour 75 g ...
Invasion of host cells by the malaria pathogen Plasmodium relies on parasite transmembrane adhesins that engage host-cell receptors. Adhesins must be released by cleavage before the parasite can enter the cell, but the processing enzymes have remained elusive. Recent work indicates that the Toxoplasma rhomboid intramembrane protease TgROM5 catalyzes this essential cleavage. However, Plasmodium ...
The effort to personalize treatment plans for cancer patients involves the identification of drug treatments that can effectively target the disease while minimizing the likelihood of adverse reactions. In this study, the gene-expression profile of 810 cancer cell lines and their response data to 368 small molecules from the Cancer Therapeutics Research Portal (CTRP) are analyzed to identify pa...
Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological conditions in humans. In the malaria parasite Plasmodium, functional insights into its kinome have only recently been achieved, with over half bei...
In recent years, the rates of obesity and related illnesses have increased in the country, with 71% of Iranian women and men suffering from overweight and obesity [1]. The epidemic of obesity and the prevalence of disorders and associated illnesses have led to an increase of 30% in health care and obesity costs in obese people compared to normal weight counterparts [2]. Therefore, harm to indiv...
the synthesis of smcl3(thf)3 from smcl3.6h2o is described. the reaction of smcl3(thf)3 with nabh4 in dry thf gave white microcrystalline tris (tetrahydroborato) tris (tetrahydrofuran) samarium (iii), sm(bh4)3(thf)3. the vibrational and magnetic properties of sm(bh4)3(thf)3 have been studied.
در شامگاه پنجشنبه بیست و پنج اسفند ماه 1384 در میانهی جادهی زابل – زاهدان، در محلی به نام تاسوکی، فاجعه تروریستی دلخراشی رخ داد که در آن بیست و دو تن از مسافران عبوری، در حالی که دستها و چشمان آنها بسته شده بود، توسط گروه موسوم به جندالله، در حالی که این گروه لباس نیروی انتظامی را به تن داشتند و ایست بازرسی ساختگی برقرار کرده بودند، به فیض شهادت نایل آمدند. هفت تن مجروح گشته و هفت تن نیز به...
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