UNLABELLED Although the mechanism of tourniquet-induced hypertension is still unclear, plasma norepinephrine concentrations continuously increase in parallel to arterial blood pressure during tourniquet inflation. Clonidine attenuates hyperadrenergic and hyperdynamic responses. We investigated the effects of clonidine on prolonged tourniquet inflation. Twenty-nine patients scheduled for electiv...

Distal radius fractures are the most common of upper limb. It is a fracture in elderly and indiction an osteosynthesis by locked plate often posed view osteopenia. Surgical fixation distal under local anesthesia with patient wide awake without tourniquet allows intraoperative testing stability active mobilization. This technique people extensive comorbidities to avoid adverse effects commonly a...

BACKGROUND The identification of potential sources of error is a crucial step for any new assessment technique. This is the case for transcutaneous variables, such as flow and arterial gases, which have been applied as functional indicators of various aspects of human health. Regarding gender, a particular subject-related determinant, it is often claimed that women present higher transcutaneous...

Arterial spin labeling (ASL) is a noninvasive magnetic resonance imaging (MRI) technique for microvascular blood flow measurement. We used a continuous ASL scheme (CASL) to investigate the hyperemic flow difference between major muscle groups in human extremities. Twenty-four healthy subjects with no evidence of vascular disease were recruited. MRI was conducted on a 3.0 Tesla Siemens Trio whol...

Introduction: Ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. As dexamethasone (Dex) has been shown to Prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. Methods: 36 male Wistar rats (200-250 gr) were chosen and divided randomly into 6 equal grou...

OBJECTIVE The purpose of the present study is to determine the performance of tourniquet use by the placement of the tourniquet's windlass on the extremity in four positions--medial, lateral, anterior, and posterior--to inform tourniquet instructors and develop best tourniquet practices. METHODS A HapMed™ Leg Tourniquet Trainer was used as a manikin to test the effectiveness of an emergency t...

The authors undertook a randomised prospective study to investigate the contribution of thigh tourniquets to the formation of intra-operative venous emboli during lower limb surgery. Patients were randomised to have a thigh tourniquet or no tourniquet and transoesophageal echocardiography was used to detect embolic signals in the right heart during and after knee arthroscopy. Three physicians b...

We have investigated whether the thigh tourniquet used during total knee replacement (TKR) influenced the development of postoperative wound hypoxia and was a cause of delayed wound healing. We allocated randomly 31 patients (31 TKRs) to one of three groups: 1) no tourniquet; 2) tourniquet inflated at low pressure (about 225 mmHg); and 3) tourniquet inflated to high pressure of about 350 mmHg. ...

BACKGROUND Gabapentin, an oral non-opioid analgesic, has been used to decrease pain after a variety of surgical procedures. We hypothesized that premedication with gabapentin would minimize tourniquet-related pain in patients receiving IV regional anesthesia (IVRA). METHODS Patients undergoing elective hand surgery with IVRA were randomly assigned to one of two study groups using a double-bli...