Results: We found high percentage of expression of CD64 on neutrophils in patients (67.73 ± 24.74) when compared with controls (8.19 ± 3.64) and also their percentage of expression was higher in culture positive sepsis (76.25 ± 29.07) than culture negative sepsis (42.21 ± 33.24). In the present study, I/T ratio >0.2 had a sensitivity, specificity, PPV, NPV and accuracy i.e. 70.0%, 72.0%, 33.3%,...

Bacteremia is a bacterial infection that enters the bloodstream. This study was designed to investigate if culture methods could detect of bloodstream and assess certain criteria for sepsis in culturable non-culturable blood samples from hospitalized patients, like C-reactive protein (CRP), lactate dehydrogenase (LDH), complete count (CBC). A total 100 patients with symptoms who resided Hilla C...

OBJECTIVE Timely detection of serious bacterial infections or prediction of sepsis and death is of paramount importance in neutropenic patients especially in oncology settings. The aim of this study was to determine a rapid and secure predictor of sepsis in severe neutropenic cancer children. METHODS In addition to blood culture, we have evaluated serum soluble CD14 on this role and measured ...

Abstract Background Neonates with sepsis may have concurrent urinary tract infection (UTI), which be asymptomatic or nonspecific symptoms. Failure to diagnose UTI, resulting in a delay of appropriate therapy, has been reported cause renal scarring, hypertension, and kidney failure among infants. This study aimed determine the contribution UTI neonatal assess different risk factors that could as...

Background: Neonatal sepsis is a serious life-threatening condition with high mortality. The early and accurate diagnosis of sepsis is one of main challenge for prevention of mortality due to sepsis in NICUs. A great effort to reduce the neonatal mortality rate is put into looking for new reliable biomarkers. Among various biomarkers, IL-6 could be promising and reliable biomarker for early dia...

Background: Neonatal sepsis is one of the common causes neonatal mortality. Blood culture gold standard procedure to confirm sepsis. However, rapid rate disease progression makes its timely diagnosis and prompt management very crucial before availability culture. The study aimed determine significance complete blood count parameters including platelet indices in diagnosing Materials Methods: Th...

OBJECTIVE Thrombocytopenia is commonly observed in very low birth weight (VLBW) neonates with sepsis. Specific platelet responses to different infectious agents have not been extensively characterized. The objectives of this study were to examine platelet counts and platelet indices in preterm neonates with culture-proven sepsis to determine if there are organism-specific platelet responses. ...

BACKGROUND Neonatal sepsis is characterised by bacteraemia and clinical symptoms caused by microorganisms and their toxic products. Gram negative bacteria are the commonest causes of neonatal Sepsis. The resistance to the commonly used antibiotics is alarmingly high. The major reason for emerging resistance against antibiotics is that doctors often do not take blood cultures before starting ant...

We investigated the validity of circulating soluble intercellular adhesion molecule-1 (slCAM-1) as an early immunological marker of neonatal sepsis as compared to C-reactive protein (CRP), immature to total neutrophils ratio (IlT) and blood culture assays. The study included 28 full term neonates with clinical manifestations of sepsis, 10 of them had suspected sepsis "Group I" with negative blo...