Physiological comparisons of cardiovascular (CV) structure/function among individuals or groups of individuals are often difficult because of differences in body dimensions. To have meaningful clinical and scientific comparisons, differences in body size must be accounted for. Although there is a plethora of data demonstrating that body size is an important determinant of CV structure/function,...

Using the collective variables (CV) method the basic relations of statistical field theory of a multicomponent non-homogeneous fluids are reconsidered. The corresponding CV action depends on two sets of scalar fields fields ρα connected to the local density fluctuations of the αth species of particles and fields ωα conjugated to ρα. The explicit expressions for the CV field correlations and the...

Understanding the functional relationship between the sample size and the performance of species richness estimators is necessary to optimize limited sampling resources against estimation error. Nonparametric estimators such as Chao and Jackknife demonstrate strong performances, but consensus is lacking as to which estimator performs better under constrained sampling. We explore a method to imp...

CONTEXT Number of the beta cells as well as their volume is a fundamental variable in the pancreatic research. OBJECTIVES This study describes a simple method for stereological estimation of the volume of the pancreas, the total volume of the islets, and the total number, as well as the mean volume, of the beta cells in rat. METHODS The primary volume of the pancreas was measured using the ...

Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved understanding of the absorption and intermediary metabolism of PP is essential. The present work describes the development and validation of a sensitive and specific method for simultaneous determin...

INTRODUCTION Investigations have brought evidence that salt intake is positively related to systolic blood pressure and that children with higher blood pressure are more susceptible to hypertension in adulthood. In developed countries the main source of salt is processed food. OBJECTIVE The aim of this paper was to determine total sodium chloride (NaCl) in average daily meal (breakfast, snack...

Determination of creatinine clearance (Ccr) is not a reliable indicator of glomerular filtration rate (GFR), owing to tubular secretion of creatinine. It has been reported that Ccr measurements can approximate true GFR after cimetidine (Ci) administration. In this study, GFR was estimated by Cockcroft and Gault's equation (C(C-G)) based on measurement of plasma creatinine, and Ccr was determine...

In principal component analysis (PCA), it is crucial to know how many principal components (PCs) should be retained in order to account for most of the data variability. A class of "objective" rules for finding this quantity is the class of cross-validation (CV) methods. In this work we compare three CV techniques showing how the performance of these methods depends on the covariance matrix str...

Using our newly developed ion-pairing reversed-phase liquid-chromatographic method for assay of indoxyl sulfate, we measured its concentration in plasma of normal subjects and patients in various degrees of renal failure. Response was linear over the range of 50 to 25 000 pmol of indoxyl sulfate injected into the chromatograph. We demonstrated the specificity of the assay for azotemic plasma by...

PURPOSE Develop an MRI method to estimate skeletal muscle oxygen consumption (VO2 ) with dynamic exercise using simultaneous measurement of venous blood flow (VBF) and venous oxygen saturation (SvO2 ). METHODS Real-time imaging of femoral VBF using a complex-difference method was interleaved with imaging of venous hemoglobin oxygen saturation (SvO2 ) using magnetic susceptometry to estimate m...