This article is linked to Mooers et al papers. To view these articles, visit https://doi.org/10.1111/apt.16457 and https://doi.org/10.1111/apt.16516 Cyclic vomiting syndrome (CVS) an increasingly recognised disorder in adults. Tricyclic antidepressants (TCAs), particularly amitriptyline, are recommended as first-line prophylactic pharmacologic treatment.1 Topiramate alternate medication along w...