BACKGROUND Gene transfer using non-viral vectors offers a non-immunogenic and safe method of gene delivery. Cellular uptake and intracellular trafficking of the nanoparticles can impact on the transfection efficiency of these vectors. Therefore, understanding the physicochemical properties that may influence the cellular uptake and the intracellular trafficking can aid the design of more effici...

Nanometer-sized functional particles are attractive for optical, electrical, magnetic, and biological applications. Recently, in addition to size, the shape of a nanoparticle was reported to be crucial, for example, to how it interacts with light, as presented by Halas and co-workers. They found that riceshaped nanoparticles made of gold and iron oxide are the most sensitive surface plasmon res...

In this article, numerical simulation is performed for mixed convection lid-driven flow of CuO -water nanofluid enclosed in a curved corrugated. Cylindrical obstacles having three different constraints: (adiabatic, cold, and heated) at its surface are considered. Internal heat generation/absorption uniform provided the vertical wall cavity. The bottom insulated, curve surfaces maintained with c...

Deterministic Aperiodic (DA) arrays of gold (Au) nanoparticles are proposed as a novel approach for the engineering of reproducible surface enhanced Raman scattering (SERS) substrates. A set of DA and periodic arrays of cylindrical and triangular Au nanoparticles with diameters ranging between 50-110 nm and inter-particle separations between 25-100 nm were fabricated by e-beam lithography on qu...

The term “nanotechnology” mainly refers more to an order of magnitude then to a specific scientific discipline. The word is used quite generally to mean the visualisation, characterization, production and manipulation of particles smaller than 100 nm. The field of nanotechnology has, however, seen the greatest progress, and some of its products are already available commercially. A nanomaterial...

A new approach for synthesizing well-defined hollow nanochanneled-silica nanosphere particles is demonstrated, and the structural details of these particles are described for the first time. Positively charged styrene copolymer nanospheres with a clean, smooth surface and a very narrow size distribution are synthesized by surfactant-free emulsion copolymerization and used as a thermal sacrifici...

Polymer field theory has emerged as a powerful tool for describing the equilibrium phase behavior of complex polymer formulations, particularly when one is interested in the thermodynamics of dense polymer melts and solutions where the polymer chains can be accurately described using Gaussian models. However, there are many systems of interest where polymer field theory cannot be applied in suc...

We have synthesized silver nanoparticles in the non-polar phase of non-aqueous microemulsions. The nanocrystals have been grown by reducing silver ions in the microemulsion cylindrical micelles formed by the reducing agent (ethylene glycol). By a careful deposit of the microemulsion phase on a substrate, the micelles align in a hexagonal geometry, thus forming a 2D array of parallel strings of ...