Single nucleotide polymorphisms (SNPs) are high-density natural sequence variations in genomes. They are considered to be the major genetic source of phenotypic variability within a given species and serve as excellent genetic markers. SNPs are useful in identifying candidate genes that contribute to disease and phenotypic traits. In non-model organisms, the application of SNPs has been limited...

CD209 is an immune receptor that plays an important role in the initiation of innate immunity and activation of adaptive immunity in mammals. However, much less is known about the immunological function of CD209 in lower vertebrates. In the present study, we examined the immune effect of a CD209 homologue (CsCD209) from the teleost fish tongue sole Cynoglossus semilaevis. CsCD209 possesses a le...

Bactericidal/permeability-increasing protein (BPI) is an important factor of innate immunity that in mammals is known to take part in the clearance of invading Gram-negative bacteria. In teleost, the function of BPI is unknown. In the present work, we studied the function of tongue sole (Cynoglossus semilaevis) BPI, CsBPI. We found that CsBPI was produced extracellularly by peripheral blood leu...

Antimicrobial peptides (AMPs) are host defense peptides that are well conserved throughout the course of evolution. Histones are classical DNA-binding proteins, rich in cationic amino acids, and recently appreciated as precursors for various histone-derived AMPs. The present study deals with identification of the potential antimicrobial peptide sequence of teleostin from the histone H2A of mari...

The aim of this study was to produce fish protein concentrate from marine Cynoglossus bilineatus, the brought local Basrah market and dried in oven at 025 °C for 06 h. chemical composition were 48.62 % (N×6.25), 19.49 fat 19.95 ash, while processed 79.56 6.38 9.51 ash. obtain yield 67.58 fish. product characterized with light brown acceptable fishy smell, also showed good strong stability after...

A 10-week feeding trial was conducted to investigate the beneficial effects of bile acids (BAs) on hepatic health status in tongue sole ( Cynoglossus semilaevis ). Three experimental diets were prepared with different levels BA inclusion commercial basal diet: control group (CT: 0 mg/kg diet), low-level (BA1: 300 and high-level (900 diet). At end trial, growth performance survival rate measured...