Background. DNA adenine methylation plays an important role in several critical bacterial processes including mismatch repair, the timing of DNA replication and the transcriptional control of gene expression. The dependence of bacterial virulence on DNA adenine methyltransferase (Dam) has led to the proposal that selective Dam inhibitors might function as broad spectrum antibiotics. Methodology...

In this paper the rapidly varied unsteady flow caused by the failure of a dam in a rectangular dry bed horizontal channel has been studied both theoretically and experimentally. Experiments with dam-break flows in smooth and rough channel have been carried out. Comparisons have been made between measured depth hydrographs at different stations along the channel and analytical solution of Ritter...

BACKGROUND DNA adenine methylation plays an important role in several critical bacterial processes including mismatch repair, the timing of DNA replication and the transcriptional control of gene expression. The dependence of bacterial virulence on DNA adenine methyltransferase (Dam) has led to the proposal that selective Dam inhibitors might function as broad spectrum antibiotics. METHODOLOG...

New air–water flow experiments were conducted in the leading edge of dam break waves. The data highlighted the chaotic nature of the surge and provided new insights in the distributions of void fraction, velocity and air/water chord sizes. The results demonstrated a highly aerated surge front with a developing turbulent boundary layer.At the leading edge, observed mean air contents exceeded 40 ...

Contemporary dam safety regulations include risk assessment at downstream flood plains and consideration of potential damages due to dam rupture, regardless of the expected probability of occurrence of such event. The aim of these kind of procedures is to increase the safety level along the valley against abnormal floods caused by dam accidents. Emergency plans for downstream flood plains, incl...