This paper presents the design, implementation and evaluation of Deadline-Driven Auctions (DDA), a novel task mapping infrastructure for heterogeneous distributed environments. DDA is primarily designed to support the hosting of Non-Player Characters (NPCs) in P2P Massively Multiplayer Online Games (MMOGs). Experimental and analytical results demonstrate that DDA provides four significant advan...

Nuclear receptors initiate transcription, interact with regulatory proteins, and are influenced by hormones, drugs, and pollutants. Herein, we discover ligand-specific mobility patterns of human estrogen receptor-alpha (ER) in living cells using diffusion-time distribution analysis (DDA). This novel method, based on fluorescence correlation spectroscopy (FCS), is especially suited to unraveling...

Typical image feature trackers employ a detect-describe-associate (DDA) or detect-track (DT) paradigm. Intuitively, a hybrid of the two approaches inherits the benefits of each approach and possibly their defects, however this has never been demonstrated formally in a more general setting. In this paper, the stability and speed of DDA, DT, and hybrid trackers are compared and discussed using a ...

The data presented in this article are related to the research article entitled "14-deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells", which the mechanistic toxicology properties of 14-deoxy-11,12-didehydroandrographolide (14-DDA) were investigated (Tan et al., 2016 [1]). This article describes the deriv...

In this paper, we address the problem of distributed learning over a decentralized network, arising from scenarios including distributed sensors or geographically separated data centers. We propose a fully distributed algorithm called random walk distributed dual averaging (RW-DDA) that only requires local updates. Our RW-DDA method, improves the existing distributed dual averaging (DDA) method...

Despite the vaccine Mycobacterium bovis Bacillus Calmette-Guérin is used worldwide, tuberculosis (TB) remains the first killer among infectious diseases. An effective vaccine is urgently required. DNA vaccine has shown prophylactic as well as therapeutic effects against TB, while its weak immunogenicity hinders the application. As a strong inducer of Th1-biased immune response, DMT, consisting ...

Objectives Heparin-binding hemagglutinin (HBHA), a mycobacterial cell surface protein, mediates adhesion to nonphagocytic cells and the dissemination of Mycobacterium tuberculosis (M. tuberculosis) from the site of primary infection. Superior expression systems are required to obtain abundant M. tuberculosis proteins for the purpose of diagnosing M. tuberculosis infection or for the immunizatio...

Increasing renal pelvic pressure increases afferent renal nerve activity (ARNA) by a PGE(2)-mediated release of substance P (SP) from renal pelvic nerves. The role of cAMP activation in the PGE(2)-mediated release of SP was studied by examining the effects of the adenylyl cyclase (AC) activator forskolin and AC inhibitor dideoxyadenosine (DDA). Forskolin enhanced the bradykinin-mediated release...

The interaction of light with multiple red blood cells was systematically investigated by the finite-difference time-domain method (FDTD). The simulations showed that the lateral multiple scattering between red blood cells is very weak and that the polarization has an almost insignificant influence on the distribution of the scattered light. The numerical results of the FDTD method were compare...