OBJECTIVES Dermal and subdermal bacterial infections, caused mainly by Staphylococcus aureus, are currently treated by systemic antibiotics. The aim of the present study was to investigate a new approach to treat deep skin and soft tissue bacterial infections by dermal application of erythromycin in an ethosomal carrier. METHODS A model for deep dermal S. aureus infection in mice was develope...

BACKGROUND Deep tissue injury (DTI) is a class of serious lesions which develop in the deep tissue layers as a result of sustained tissue loading or pressure-induced ischemic injury. DTI lesions often do not become visible on the skin surface until the injury reaches an advanced stage, making their early detection a challenging task. THEORY Early diagnosis leading to early treatment mitigates...

is it possible to discharge a 2-3 hours, 1134 g weight breast feeding newborn in 24 -36 hours from hospital?   yes, in materno pediatric hospital located in bogatto-clombia it is a routine. it is an approach to prevent high costs and nosocomial infections. it also used to establish a deep relationship based on natural and instinct process.   newborns who are in satisfactory clinical situations,...

Abstract Background The outcomes of immediate autologous breast reconstruction (IABR) after partial mastectomy followed by postoperative radiotherapy (RT) in terms aesthetics, treatment-related complications, and local control are unclear. In this study, we evaluated the efficacy IABR with or without RT, thus impact radiation on flap transfer. Method A retrospective cohort study involving conse...

A fully automatic prediction for peptide retention time (RT) in liquid chromatography (LC), termed as DeepRT, was developed using deep learning approach, an ensemble of Residual Network (ResNet) and Long Short-Term Memory (LSTM). In contrast to the traditional predictor based on the hand-crafted features for peptides, DeepRT learns features from raw amino acid sequences and makes relatively acc...

BACKGROUND Laxity and rhytidosis of eyelid skin as a result of photoaging is a frequent cosmetic concern. Fine lines and deep wrinkles may not be optimally addressed with traditional ablative carbon dioxide (CO(2)) resurfacing. Modern devices allow for surface fractional ablation and deep fractional ablation with narrow treatment columns that target deep dermal layers. OBJECTIVES To examine t...

The aim of this study was to describe the scheme, surgical procedures, and clinical outcomes for the early repair of deep wounds of the posterior talocrural region in extensively burned patients with a method combining a superficial temporal fascia free flap with thin split-skin grafting. From January 2013 to February 2016, 9 extensively burned patients with deep tissue defects of the posterior...

In this study, a multi-task deep neural network is proposed for skin lesion analysis. The proposed multi-task learning model solves different tasks (e.g., lesion segmentation and two independent binary lesion classifications) at the same time by exploiting commonalities and differences across tasks. This results in improved learning efficiency and potential prediction accuracy for the task-spec...

PURPOSE To report the efficacy of Hydrosorb® versus control (water based spray) as topical treatment of grade 1-2 radiodermatitis in patients (pts) treated for early stage breast cancer (BC) with normo fractionated radiotherapy (RT). PATIENTS AND METHODS BC pts were randomized to receive either Hydrosorb® (A) or water based spray (B). The primary endpoint was local treatment failure defined a...