Incubation of human leukocytes with dehydroascorbate (DHA) results in an increase in their reduced ascorbate (AA) content and hexose monophosphate shunt (HMS) activity, independent of oxygen supply. Incubation with AA induces these changes only in the presence of oxygen. The increase in HMS activity observed as cell AA increases by 1 micromol is the same during incubation with either DHA or AA....

Scorbutic guinea pig neutrophils (PMN) were found to produce H2O2 and kill Staphylococcus aureus as well as control PMN, suggesting that ascorbate does not contribute significantly to phagocyte H2O2 production or bacterial killing. Total and reduced ascorbate contents of human PMN was observed to fall upon phagocytosis, whereas dehydroascorbate increased to a lesser extent. These observations a...

heavy metal accumulation in plants causes induction of oxidative stress. plants have severaldefense systems involved in detoxifying free radicals. in the present research we treated the 15 d.seedlings of b. napus grown in pots with different concentrations of cadmium (0, 10, 50 and 100 μm) ascdcl2. after 3 weeks we measured malondealdehyde (mda) content in leaves of treated plants as anindicati...