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OBJECTIVE Dengue is a worldwide public health problem with approximately 50 million cases reported annually. The World Health Organization proposed a revised classification system in 2008 to more effectively identify the patients who are at increased risk of complications from dengue. Few studies have validated this new classification system in clinical practice. We conducted a cross-sectional ...

Dengue is an important viral illness which has the potential to progress into dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Leucopenia and throm-bocytopenia are the hallmarks of acute dengue which normalise with recovery [1]. Progression from thrombo-cytopenia to severe thrombocytosis is uncommon. We describe a patient presenting with acute dengue, who developed extreme reactiv...

Dengue fever is a febrile illness caused by an arbovirus transmitted the Aedes aegypti mosquito. It occurs as aseasonal epidemic every year in Pakistan. Apart from and its associated hemorrhagic complication,dengue with multi-system involvement their respective complications, including myriadneurological complications. In this case report we describe two patients who developed acute viral myosi...

Dengue virus (DENV) is a positive-sense, single-stranded RNA virus that is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Greater than 100 million cases of dengue fever occur annually and over 2 billion people live in areas at risk for dengue transmission. There are four phylogenetically and serologically distinct DENV, which are capable of human-to-mosquito-to-human transmission...

Dengue, a global health threat, is a leading cause of morbidity and mortality in most tropical and subtropical countries. Dengue can range from asymptomatic, relatively mild dengue fever to severe and life-threatening dengue hemorrhagic fever. Disease severity and outcome is largely associated with the host immune response. Several candidate vaccines in clinical trials appear promising as effec...

A dengue fever surveillance study was conducted at three medical facilities located in the low-income district of San Javier in Medellin, Colombia. During March 2008 to 2009, 781 patients with fever regardless of chief complaint were recruited for acute dengue virus infection testing. Of the 781 tested, 73 (9.3%) were positive for dengue infection. Serotypes DENV-2 (77%) and -3 (23%) were detec...

Dengue virus (DENV) is a positive-sense, single-stranded RNA virus that is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Greater than 100 million cases of dengue fever occur annually and over 2 billion people live in areas at risk for dengue transmission. There are four phylogenetically and serologically distinct DENV, which are capable of human-to-mosquito-to-human transmission...

The World Health Organization (WHO) scheme for classification of dengue severity was evaluated in a three-year study of 1,671 confirmed dengue cases in three Nicaraguan hospitals. The WHO classification of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) was compared with the presence of hemorrhagic manifestations, signs of vascular permeability, marked thrombocytopenia, and shock...

In Pernambuco, the first dengue cases occurred in 1987. After a seven-year interval without autochthonous cases, a new epidemic occurred in 1995. Important aspects of the dengue epidemics during the period 1995-2006 have been analyzed here, using epidemiological, clinical and laboratory data. A total of 378,374 cases were notified, with 612 confirmed cases of dengue hemorrhagic fever and 33 dea...