This research was purposely to study and determine the physicochemical characteristics, sensory hypocholesterolemic effects of purple sweet potato bread made from flour, starch, fiber-rich flour starch processing waste on white male species Wistar rats conducted in vivo. used a non-factorial randomized block design model with treatment 100% standard feed, 25% mixture bread, combination 50% heal...

OBJECTIVE Progression of carotid intima-media thickness (CIMT) is a surrogate indicator for the early stages of atherosclerosis. METHODS The study investigated relationships between baseline lipoprotein cholesterol, triglyceride (TG), and apolipoprotein (Apo) B levels assessed with density gradient ultracentrifugation (DGU) and progression of posterior wall common CIMT in men (45-75 years of ...

Positive assortative mating of baboons (Papio sp.) based on elevation of serum cholesterol concentrations in response to a cholesterol- and saturated fat-enriched diet produced 64 progeny (30 high line; 34 low line). When the animals were 3 to 4 years of age, we tested their lipoprotein cholesterol responses to dietary cholesterol and fat in a factorial experiment with two levels of dietary cho...

Lecithin:cholesterol acyltransferase (LCAT) is a key plasma enzyme in cholesterol and high density lipoprotein (HDL) metabolism. Transgenic rabbits overexpressing human LCAT had 15-fold greater plasma LCAT activity that nontransgenic control rabbits. This degree of overexpression was associated with a 6.7-fold increase in the plasma HDL cholesterol concentration in LCAT transgenic rabbits. On a...

Lipoprotein cholesterol and triglyceride concentrations were compared in diabetic and nondiabetic Pima Indians, a homogeneous population with a high occurrence of noninsulin-dependent diabetes mellitus. Data were available on 690 subjects with diabetes or impaired glucose tolerance. Total and very low density lipoprotein (VLDL) triglycerides were approximately 150% of the nondiabetic values, bu...

1833 Elevated levels of circulating high-density lipoprotein cholesterol (HDL-C) have long been thought to be associated with reduced coronary artery disease (CAD) risk. This concept has led to the HDL hypothesis: increasing HDL-C would be a key addendum in the prevention of CAD, in addition to reducing circulating low-density lipoprotein cholesterol levels. In theory, increasing HDL-C should i...

OBJECTIVE Peroxisome proliferator-activated receptor-δ-induced upregulation in skeletal muscle fatty acid oxidation would predict the modulation of lipid/lipoproteins. METHODS AND RESULTS GW501516 (2.5, 5.0, or 10.0 mg) or placebo was given for 12 weeks to patients (n=268) with high-density lipoprotein (HDL) cholesterol <1.16 mmol/L. Fasting lipids/apolipoproteins (apos), insulin, glucose, an...

Purpose To evaluate lipids and C-reactive protein serum levels in patients with pseudoexfoliation syndrome (PEX) in the Polish population. Methods 96 patients were studied with PEX and 79 control subjects. Total cholesterol, triglycerides, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, non-HDL-cholesterol and CRP serum levels, and TG/HDL-C and TC/HDL-C ...

Phospholipid transfer protein (PLTP) is a member of the lipid transfer/lipopolysaccharide-binding protein family that first attracted attention by virtue of its functions in intravascular lipoprotein metabolism. These include its key role in mediating transfer of phospholipids from very-lowdensity lipoprotein to high-density lipoprotein (HDL) in conjunction with very-low-density lipoprotein lip...

Phospholipid transfer protein (PLTP) is a member of the lipid transfer/lipopolysaccharide-binding protein family that first attracted attention by virtue of its functions in intravascular lipoprotein metabolism. These include its key role in mediating transfer of phospholipids from very-lowdensity lipoprotein to high-density lipoprotein (HDL) in conjunction with very-low-density lipoprotein lip...