This paper studies the distribution of emergency relief for electric vehicles (EVs), which considers energy saving, multi-depot, and vehicle routing problems with time windows, named saving-oriented multi-depot problem windows (ESMDVRPTW). Our aim is to find routes EVs such that all shelter demands are fulfilled during their total cost traveled by fleet minimized. To this end, we formulate ESMD...

Scientific support depot location and reasonable spare parts transportation are the keys to improving level of complex systems. The current equipment system has problems chaotic warehouse layout low efficiency parts. reliability completeness parts’ historical data hard believe. In order deal with cognitive uncertainty caused by asymmetry data, this paper adopts theory optimize volume. Under con...

OBJECTIVES To compare the pharmacodynamics and tolerability of the new goserelin acetate 10.8-mg depot with the 3.6-mg depot in patients with advanced prostate cancer during the first 3 months of therapy. METHODS One hundred sixty patients were randomized in two comparative studies to receive either the 10.8-mg goserelin acetate depot every 12 weeks or the 3.6-mg goserelin acetate depot every...

Long-acting depot antipsychotics were developed specifically to promote treatment adherence (compliance) and they are a valuable option for patients requiring maintenance medication for schizophrenia. Depot use has fallen in recent years, perhaps owing to the introduction of oral atypical antipsychotics. Psychiatrist and patient acceptance of depot medication is variable. The depot formulation ...

long protocol of gonadotropin-releasing hormone-analougue (gnrh-a) can result in the formation of ovarian cyst by the transient initial stimulatory effect which increases the levels of both follicle-stimulating hormone (fsh) and luteinizing hormone (lh). these cysts require surgical drainage or result in poor ovarian response. ovarian cyst formation can be prevented by taking oral contraceptive...

Transportation problems appear in many practically highly relevant areas of our daily life. In this work we deal with a generalized variant of the classical Vehicle Routing Problem (VRP), namely the Periodic Vehicle Routing Problem with Time Windows (PVRPTW), for which only few specific solution techniques have been described in the literature. The basis forms the VRP which is defined on a comp...

This paper examines a practical transportation model known as the Open Vehicle Routing Problem (OVRP). OVRP aims at designing the minimum cost set of routes originating from a central depot for satisfying customer demand. Vehicles do not need to return to the depot after completing their delivery services. In methodological terms, we propose an innovative local search metaheuristic which examin...

Providing appropriate home health care is one of the increasing concerns in organizations. Home Health Care provides various services for disabled or elderly individuals at their homes. Also, deal with current critical situation coronavirus disease (COVID-19) due to limited capacity hospitals and feeling insecurity crowded places, more recommended. This paper addresses a Routing Scheduling Prob...