BACKGROUND Over the past decade, studies of the effectiveness of pharmacological treatment for depression have often been based on research designs intended to measure efficacy, and for this reason the results are of limited generalizability. Research is needed comparing the clinical and economic outcomes of antidepressants in day-to-day clinical practice. METHODS A six-month randomised prosp...

Aim: Homocysteine and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism have been investigated as risk factors for depression and ACS separately, but not for depression comorbid with ACS. This study aimed to investigate whether homocysteine and MTHFR gene are associated with occurrence of depressive disorder in ACS. Methods and results: A sample of 969 patients with recent ACS ...

Aim: Homocysteine and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism have been investigated as risk factors for depression and ACS separately, but not for depression comorbid with ACS. This study aimed to investigate whether homocysteine and MTHFR gene are associated with occurrence of depressive disorder in ACS. Methods and results: A sample of 969 patients with recent ACS ...

sheehan’s syndrome or simmond’s disease is a rare endocrine disorder seen in clinical practice. the clinical spectrum is diverse and a high index of suspicion together with a good clinical acumen and proper diagnostic approach helps in early diagnosis and prompt treatment of this endocrinopathy. sheehan’s syndrome presenting as a major depressive disorder finds less mention in the literature. t...

purpose: to investigate the effectiveness of metacognitive therapy in patients with major depressive disorder. the population of this study included all patients admitted to the army hospital no. 520 diagnosed with major depressive disorder from which 30 individuals were selected by using random sampling into experimental and control groups (n = 15 experimental and n = 15 control). materials an...

As a result of their increasing prevalence, diabetes and depression, together with population growth aging, are growing public health concerns. Diabetes depressive disorder may occur on the basis common pathophysiology interact each other. Complex environmental, social, behavioral, emotional factors influence care. In particular, maintaining psychological well-being for people is foundation ach...

Periodontal disease, a bacterially mediated inflammatory disease of the gingival and adjacent periodontal attachment apparatus, represents, after dental caries, the leading cause of tooth loss among adults in developed countries due to the destruction of the periodontal ligament and the loss of the adjacent supporting bone, the tissues which support the teeth (Pihlstrom et al., 2005). Depressiv...