This vignette provides an overview of the Bioconductor package ASSIGN for signaturebased profiling of heterogeneous biological pathways. ASSIGN (Adaptive Signature Selection and InteGratioN) is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway si...

Abstract After the opening up of banking sector to domestic and foreign capitals which is approved by Chinese government, China Banking Regulatory Commission (CBRC) has permitted city commercial banks diversify geographically. Since this deregulation in 2006, began geographically occupy market acquire more financial resources. To examine causal relationship between geographical diversification ...

COI: REDD1 monoclonal antibody reported herein is now being sold by Bethyl laboratories. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract mTORC1 is implicated in cell growth control and is extensively regulated. We previously reported that in response to hypoxia, mTORC1 is inhibited by REDD1. REDD1 is upregulated by HIF-1, and forced...

nds that on almost every conceivable measure, union power has declined. The paper addresses the practical impact of changes in the environment for unionism and fi nds that unions in 2004 are doing ‘more’ with ‘less’ than they were in the late 1980s. However, an examination of key aspects of unionism during the late 1990s and early 2000s, suggests that while the condition of Australian trade uni...

In similar fashion to western countries, ASEAN countries are also gearing up towards deregulation. Despite potentially different motivating drivers, the ultimate objectives are free market competition leading to efficient pricing signals as well as providing customers with the freedom to choose their electricity provider and benefit from competitive prices. This paper provides an ASEAN electric...