نتایج جستجو برای: derived microparticle

تعداد نتایج: 482892  

Journal: :iranian journal of blood and cancer 0
hemmati t farsinezhad a managhchi mr toogeh g faranoush m

background: activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. this study was conducted to determine microparticles formation and platelet shrinkage ...

2017
Qigui Li Lisa Xie Diana Caridha Qiang Zeng Jing Zhang Norma Roncal Ping Zhang Chau Vuong Brittney Potter Jason Sousa Sean Marcsisin Lisa Read Mark Hickman

Decoquinate nanoparticle and microparticle suspended in an oily vehicle to retard drug release are evaluated for long-term malaria prophylaxis. Pharmacokinetic studies in normal animals and antimalarial efficacy in liver stage malaria mice were conducted at various single intramuscular-decoquinate doses for 2, 4, 6, or 8 weeks prior to infection with P. berghei sporozoites. The liver stage effi...

Journal: :Radiation protection dosimetry 2011
J S Eakins J Th M Jansen R J Tanner

Uranium microparticles (radii: 50 nm-1.25 μm) were modelled surrounded by tissue and exposed to natural background radiation, in order to investigate potential dose enhancements from photon interactions. Generally, the results depended on the microparticle size. For a 0.5 μm radius microparticle in an isotropic field, it was found that the combined photon/electron doses deposited in 1 and 10 μm...

Journal: :Revista espanola de cardiologia 2015
Silvia Montoro-García Eduard Shantsila Benjamin J Wrigley Luke D Tapp José Abellán Alemán Gregory Y H Lip

INTRODUCTION AND OBJECTIVES Microparticles are markers for cell activation and apoptosis and could provide valuable information that is not available from clinical data. This study assesses the clinical and biological relationship of small-sized microparticles in different forms of ischemic systolic heart failure and their relation to markers of inflammation and repair. METHODS We compared 49...

2015
Laily D. Zubairova Roza M. Nabiullina Chandrasekaran Nagaswami Yuriy F. Zuev Ilshat G. Mustafin Rustem I. Litvinov John W. Weisel

Despite the importance of circulating microparticles in haemostasis and thrombosis, there is limited evidence for potential causative effects of naturally produced cell-derived microparticles on fibrin clot formation and its properties. We studied the significance of blood microparticles for fibrin formation, structure, and susceptibility to fibrinolysis by removing them from platelet-free plas...

2016
Filiz Şimşek Orhon Nejat Akar Yonca Eğin Betül Ulukol Sevgi Başkan

Microparticles express phospholipids and support thrombin generation, which increases with age [1,2]. In a recently published study, we showed age-dependent changes in thrombin generation parameters in a healthy infant population aged 1-24 months [3]. The aim of this present study was to compare the levels of both indirect microparticle activity and thrombin generation parameters of healthy inf...

2013
Şinasi ÖZSOYLU

95 To the Editor, Baytan et al.’s case report entitled, Cerebellar granulocytic sarcoma: A case report (2012; 19: 177-180), [1] provides an opportunity for me to remind physicians that short-course megadose methylprednisolone (MDMP: 30 mg/kg for 3 d, then 20 mg/kg for 4 d each dose administered over the course of 10-15 min intravenously or orally; calculated dose of powder put into a spoon and ...

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