The clinical data related to Rheumatoid Arthritis has shown that there is more number of males (60%) than females (40%) during January month at KGH, Visakhapatnam, India. The patients also have more number of Neutrophils (72%) and Lymphocytes (18%) and less number of Eosinophils (10%) and Monocytes (0%) suffering from Rheumatoid Arthritis. Based on docking results Leflunomide and Desoxycorticos...

Futcher and Schroeder (1) and Warren and Stead (2) suggested that changes in endocrine activity might be present in congestive heart failure and might explain some of the symptoms such as edema and sodium retention. Merrill, Morrison, and Brannon (3) found an increased concentration of renin in the renal venous blood. No other reports of endocrine changes in congestive heart failure appear in t...

Despite various theories on the mechanism of the appearance of DOCA escape, the nature of this phenomenon still remains unknown. In this study the influence of a high or low potassium diet on the sodium retaining effect of DOCA was investigated in dogs. A low potassium diet facilitated the appearance of DOCA escape, while a high potassium diet delayed its appearance. The rise of blood pH was fa...

The effects of cholesterol dosage, cortisone, and desoxycorticosterone acetate on total serum cholesterol, lipoproteins, and atherosclerosis were studied over a period of 112 days in thirty-two rabbits. Cholesterol was administered by feeding the rabbits diets containing 0.063, 0.25, and 1.0 per cent cholesterol At intervals measurements were made of total serum cholesterol and of low density l...

DCA was administered in two separate experiments to rats in amounts sufficient to cause marked elevation of the blood pressure. It was then abruptly withdrawn. Following this treatment, observations of blood pressure, blood urea nitrogen, plasma potassium, and plasma volume were carried out for over a year. Approximately one-third of the animals so treated developed a sustained, permanent hyper...

The hypertension occurring in association with adrenal cortical hyperfunction (Cushing's syndrome and congenital adrenal hyperplasia), the difficulty in establishing or maintaining experimental hypertension in the absence of the adrenal gland (1-3), and the amelioration of human "essential" hypertension by adrenalectomy (4) or the development of adrenal insufficiency (5) have led several invest...