BACKGROUND/AIMS In recent years, one of technical attempts to improve biocompatibility and tolerability of the hemodialysis procedure is the substitution of acetate in dialysis solution with citrate. The aim of our study was to compare two dialysis solutions: traditional bicarbonate dialysis solution containing acetate (3 mmol/L) (solution A); and (solution C) commercially produced citrate-enri...

During the standard heat sterilization process of the lactate–buffered peritoneal dialysis solutions, glucose (an osmotic active substance) degrades to form compounds called glucose degradation products which are cytotoxic and affect the survival of the peritoneal membrane. This case presentation is based on an observation of 224 aseptic peritonitis cases of unknown etiology. For the purpose of...

during the standard heat sterilization process of the lactate–buffered peritoneal dialysis solutions, glucose (an osmotic active substance) degrades to form compounds called glucose degradation products which are cytotoxic and affect the survival of the peritoneal membrane. this case presentation is based on an observation of 224 aseptic peritonitis cases of unknown etiology. for the purpose of...

Numerous studies have confirmed beneficial effects of polyglucose dialysis solution (PG-DS), an amino acid dialysis solution (AA-DS), and bicarbonate (bic) or bicarbonate/lactate (bic/lac) buffered solutions on selected components of peritoneal bioavailability or clinical parameters of peritoneal dialysis (PD) patients. Few adverse effects have also been described. A question arises whether the...

The changes in plasma and dialysate amino acids (AA) in 7 continuous ambulatory peritoneal dialysis (CAPD) children after dialysis with a 1% AA solution were compared with a glucose-containing solution. During the AA-exchange, the plasma levels of individual AA reached their peaks after 1 h, with their percentage increments significantly correlated (p less than 0.001) with the ratio of the amou...

Dialysis and adsorption processes are commonly implemented in liver support devices for the removal of albumin-bound toxins such as tryptophan. In this work, dialysis and adsorption of tryptophan from albumin-containing solutions were investigated; in particular, the effect of albumin concentration on both processes was analysed. Theoretical models accounting for albumin-tryptophan binding were...

Initiation of peritoneal dialysis (PD) induces several changes both locally in the peritoneum and systemically. We performed a pilot study to generate insights into the early clinical and systemic changes after catheter insertion and the first weeks of PD. The study included 11 new PD patients (7 men, 4 women). The study period started just before implantation of the Tenckhoff catheter and fini...

The cost of producing the dialysis solutions is approximately one-fourth that of proprietary dialysis fluids. This includes the price of labour, but not that of laboratory determinations for quality control. The total price of the initial equipment such as mixingtanks, a pump, filter holders, and a dozen carboys is about £625 ($1,500). Many hospital pharmacies carry these items as part of their...