OBJECTIVE In this study, we analyzed the fatty acid profile of brains and plasma from male and female mice fed chow or a western-style high fat diet (WD) for 16 weeks to determine if males and females process fatty acids differently. Based on the differences in fatty acids observed in vivo, we performed in vitro experiments on N43 hypothalamic neuronal cells to begin to elucidate how the fatty ...

twenty-four holstein male calves (bw=217±57kg) were employed to evaluate the effects of rapeseed oil supplementation on growth, carcass as well as on meat quality and fatty acid content of longissimus thoracis muscle in a completely randomized design. the calves were divided into three groups and allocated to three diets of: a corn/barley-based diet (c); a diet containing 2% (dm basis) rapeseed...

Most migrating birds accumulate lipid stores as their primary source of energy for fueling long distance flights. Lipid stores of birds during migration are composed of mostly unsaturated fatty acids; whether such a fatty acid composition enhances exercise performance of birds is unknown. We tested this hypothesis by measuring metabolic rate at rest and during intense exercise in two groups of ...

OBJECTIVES To ascertain the effects of dietary omega-3 (n-3) fatty acids on biochemical and histopathologic components of the inflammatory stage of wound healing. ANIMALS 30 purpose-bred Beagles. PROCEDURE Dogs were allotted to 5 groups of 6. Each group was fed a unique dietary fatty acid ratio of omega-6 to n-3--diet A, 5.3:1; diet B, 10.4:1; diet C, 24.1:1; diet D, 51.6:1; and diet E, 95....

The anemia of sickle cell disease is associated with a severe inflammatory vasculopathy and endothelial dysfunction, which leads to painful and life-threatening clinical complications. Growing evidence supports the anti-inflammatory properties of ω-3 fatty acids in clinical models of endothelial dysfunction. Promising but limited studies show potential therapeutic effects of ω-3 fatty acid supp...

The objective of this study was to compare the effects of linoleic acid (cis,cis-C18:2(n-6)) and its hydrogenation products elaidic (trans-C18:1(n-9)) and stearic acid (C18:0) on serum lipoprotein levels in humans. Twenty-six men and 30 women, all normolipemic and apparently healthy, completed the trial. Three experimental diets were supplied to every subject for 3 weeks each, in random order (...

A recirculating liver perfusion system was used to study the effects of dietary selenium (Se) on the hepatic secretion of very-low-density lipoprotein (VLDL). The perfusate from livers of rats fed on a Se-deficient diet incorporated about 50% more [1-14C]oleic acid into triacylglycerol (TG) and cholesteryl esters (ChoEs) than did the perfusate from livers of rats fed on a Se-supplemented diet. ...

The aim of this study is to investigate the mechanism behind the slow increase in fat oxidation on a high-fat diet. Therefore, we determined 24-h substrate oxidation using respiration chambers and the rate of appearance and oxidation of plasma-derived fatty acids in seven healthy nonobese men (age 23 +/- 2 years, height 1.85 +/- 0.03 m, weight 70.4 +/- 2.3 kg, % body fat 13 +/- 1). Before testi...

the objective of this study was to evaluate the effect of five dosage of vitamin c (0, 50, 250, 750 and 1500 mg vitamin c per kg diet) on fatty acid composition of caspian brown trout fry (salmo trutta caspius). fish (initial average body weight of 0.1 ± 0.02 g) were fed by formulated diets for 6 weeks in triplicate. the findings of growth parameters and survival showed significant difference a...

the aim followed in this study was to investigate the effects of soybean oil (high in c18:2 n-6, an omega-6 fatty acid) and fish oil (high in epa 20:5 n-3 and dha 22:6 n-3, omega-3 fatty acids) on meat quality and on the fatty acid profiles in goat kids. twenty-four male kids were allocated through stratified randomization and on the basis of body weight (19.43±1.2 kg) into three equal groups. ...