In E. coli, 10 to 15% of growing bacteria produce dimeric chromosomes during DNA replication. These dimers are resolved by XerC and XerD, two tyrosine recombinases that target the 28-nucleotide motif (dif) associated with the chromosome's replication terminus. In streptococci and lactococci, an alternative system is composed of a unique, Xer-like recombinase (XerS) genetically linked to a dif-l...

A method for analyzing test item responses is proposed to examine differential item functioning (DIF) in multiple-choice items through a combination of the usual notion of DIF, for correct/incorrect responses and information about DIF contained in each of the alternatives. The proposed method uses incomplete latent class models to examine whether DIF is caused by the attractiveness of the alter...

Differentiation-inducing factor 1 [DIF-1; 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-hexan-1-one] induces stalk cell differentiation during Dictyostelium development. It is present as a gradient in the multicellular slug, its lowest concentration being in the anterior. Here we demonstrate the existence of a localized sink for DIF-1, also in the anterior of the slug, which could be responsib...

described a three-step approach used by researchers and practitioners attempting to identify biased test items: First, statistical methods are used to find items for which there are unexpected differences in performance between two groups (e.g., men and women). Second, each potentially biased item is examined for the reasons it is relatively more difficult for a particular group of examinees. T...

Drip fertigation with reduced fertilizer and water inputs has been widely used in greenhouse vegetable production China. However, farmers usually do not apply additional organic material a high carbon content, although soil (SOC) concentrations are mostly below the optimum level for production. Returning straw or biochar to fields is an effective strategy sustainability environmental friendline...

We have reported that the differentiation-inducing factors (DIFs) DIF-1 and DIF-3, morphogens secreted from Dictyostelium discoideum, inhibit proliferation of several cancer cells via suppression of the Wnt/beta-catenin signaling pathway. However, the target molecules of DIFs involved in the anti-proliferative effects are still unknown. In the present study, DIF-1-tethered resins were synthesiz...

We investigated measurement equivalence in two antisocial behavior scales (i.e., one scale for adolescents and a second scale for young adults) by examining differential item functioning (DIF) for respondents from single-parent (n = 109) and two-parent families (n = 447). Even though one item in the scale for adolescents and two items in the scale for young adults showed significant DIF, the tw...

The dataflow interchange format (DIF) is a textual language that is geared towards capturing the semantics of graphical design tools for DSP system design. A key objective of DIF is to facilitate technology transfer across dataflow-based DSP design tools by providing a common, extensible semantics for representing coarse-grain dataflow graphs, and recognizing useful sub-classes of dataflow mode...

Separation of somatic cells from germ-line cells is a crucial event for multicellular organisms, but how this step was achieved during evolution remains elusive. In Dictyostelium discoideum and many other dictyostelid species, solitary amoebae gather and form a multicellular fruiting body in which germ-line spores and somatic stalk cells differentiate, whereas in Acytostelium subglobosum, acell...