the complexity of multiple sclerosis (ms) and the incompetence of a large number of promise treatments in ms urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses and induction of local endogenous regeneration. emerging data propose that hematopoietic, mesenchymal and neural stem cells have the potential to restore self-tolerance, to pro...

background dox is a powerful chemotherapeutic agent used in the treatment of solid tumors and malignant hematological diseases. however, its cardiac toxicity limits the clinical usefulness of this drug. previous reports have shown corticosteroids induce a cytoprotective effect on cardiomyocytes. mouse transgenic embryonic stem cell-derived pure cardiomyocytes may be considered as a model for as...

background the ability to follow the distribution and migration of biologically active cells in human is essential for the development of cell-based therapies and diagnostics. nuclear medicine imaging is widely applied in clinic as an attractive technique for in vivo wbc and stem cell tracking. the aim of this study was to evaluate prosthesis infection of a 51 years old man with previous histor...

background the aim of this clinical trial was the assessment of safety and efficacy of submocosal and periurethral injections of peripheral blood derived autologous stem cells along with platelets, and focused on outcome for six months. methods an open, prospective study was conducted on 10 patients presenting with stress urinary incontinence. at the baseline (pre-operative), 1, 3 and 6 months ...

Basilar skull fractures in horses can occur at any age, although young are particularly prone to this type of injury. This manuscript describes two foals with a basisphenoid bone fracture, clinical presentations ranging from mild neurological signs up severe compromise. The absence does not exclude fracture bone, as lethargy and retropharyngeal swelling may be the only signs. Radiography help d...