We have used the complement-fixing antibody consumption ( CFAC ) test to detect small concentrations of IgG on red blood cells from patients with hemolytic anemias that are not thought to be caused by an immune mechanism. Although patients with hereditary spherocytosis, pyruvate kinase deficiency, and mechanical hemolytic anemias generally had normal concentrations of IgG bound to their red cel...

Several hemolytic markers are available to guide the differential diagnosis and to monitor treatment of hemolytic conditions. They include increased reticulocytes, an indicator of marrow compensatory response, elevated lactate dehydrogenase, a marker of intravascular hemolysis, reduced haptoglobin, and unconjugated hyperbilirubinemia. The direct antiglobulin test is the cornerstone of autoimmun...

We report a case of hemolytic anemia as an initial manifestation of hepatitis A virus infection. On admission, the patient had anemia, reticulocytosis, and direct and indirect hyperbilirubinemia. On subsequent examination, he had both glucose-6-phosphate dehydrogenase deficiency (G6PD) and autoimmune antibodies.

Cellulitis is frequently seen in ambulatory care settings and is often responsive to empiric therapy directed against Staphylococcus aureus and group A b-hemolytic streptococcus. Ideally, blood culture susceptibility by offending pathogens should direct antimicrobial therapy, but their low yield in skin infections may render them clinically useless. We therefore reviewed the available evidence ...

A hemolytic toxin related to thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH), produced by Kanagawa-phenomenon-negative Vibrio parahaemolyticus is suspected of playing an important, but yet-to-be-elucidated role in diarrhea caused by this organism. In cultured human colonic epithelial cells, TRH increases Cl(-) secretion, followed by elevation of intracellular calcium.

The. inbred NZB/BL mouse has been shown by Bielschowsky, Helyer, and Howie (1959) to develop auto-immune haemolytic anaemia spontaneously, and this disorder has been considered to be genetically determined (Holmes and Burnet, 1966). Burnet and Holmes (1962) described a characteristic thymic change in this 'auto-immune' strain of mice; and certain renal lesions have been noted (Holmes and Burnet...

BACKGROUND Naturally occurring alloantibodies produced against A and B red cell antigens in cats can cause acute hemolytic transfusion reactions. Blood incompatibilities, unrelated to the AB blood group system, have also been suspected after blood transfusions through routine crossmatch testing or as a result of hemolytic transfusion reactions. HYPOTHESIS Incompatible crossmatch results among...

A four-dimensional intermolecular potential-energy surface has been calculated for the HCN-HCl complex, with the use of the coupled cluster method with single and double excitations and noniterative inclusion of triples. Data for more than 13,000 geometries were represented by an angular expansion in terms of coupled spherical harmonics; the dependence of the expansion coefficients on the inter...

Introduction: However human oral cavity consist a mass of microorganisms, some alteration such as application the complete removable denture with poor oral hygiene in edentulous patients may cause overgrowth of several opportunistic microorganisms resulted denture stomatitis. The aim of present study was to compare the dominant oral micro-flora between edentulous denture users with dentate elde...

INTRODUCTION Mixed warm and cold autoimmune hemolytic anemia runs a chronic course with severe intermittent exacerbations. Therapeutic options for the treatment of hemolysis associated with autoimmune hemolytic anemia are limited. There have been only two reported cases of the effective use of rituximab in the treatment of patients with mixed autoimmune hemolytic anemia. We report a case of sev...