The deleted in liver cancer 1 (DLC-1) gene encodes a GTPase activating protein that acts as a negative regulator of the Rho family of small GTPases. Rho proteins transduce signals that influence cell morphology and physiology, and their aberrant up-regulation is a key factor in the neoplastic process, including metastasis. Since its discovery, compelling evidence has accumulated that demonstrat...

During human early pregnancy, fetus-derived trophoblasts come into direct contact with maternal immune cells at the maternofetal interface. At sites of placental attachment, invasive extravillous trophoblasts encounter decidual leukocytes (DLC) that accumulate within the decidua. Because we first found chemokine CXCL16 was highly expressed in and secreted by the first-trimester human trophoblas...

background autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. most of the cases are associated with viral or bacterial infections. in some cases, aiha can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. case report especially in children younger than 2 y...

The friction of diamond and diamond-like carbon (DLC) materials was evaluated in reciprocating sliding wear testing under controlled relative humidity. The testing conditions were a displacement stroke of 100 mm, an oscillatory frequency of 8Hz and a normal load of 2N. The coefficient of friction of diamond and hydrogen-free DLC (a-C) coatings against a corundum sphere in the steady regime decr...

AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization. METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients were seen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tu...

DLC-1 (deleted in liver cancer-1) is a potential tumor suppressor gene, which is inactive in liver carcinogenesis. To observe the effects of DLC-1 gene expression on cell proliferation and migration in the human colon cancer cell line, RNAi Lipo-recombinant of the DLC-1 gene (pGCsil-DLC-1) was constructed and transduced into LoVo cells which are positive for DLC-1 gene expression. Results showe...

Diamond-like carbon (DLC), also known as amorphous hydrogenated carbon (a-C:H), is a class of materials with excellent mechanical, tribological and biological properties. By the addition of other elements into the DLC all of these properties can be changed within a certain range. It will be shown that the ratios of the different proteins adsorbed on the surface can be influenced by the addition...

Various PVD (physical vapor deposition) hard coatings including nitrides and metal-doped diamond-like carbons (Me-DLC) were applied in plastic injection and die-casting molds to improve wear resistance and reduce sticking. In this study, nitrides hcp-AlN (hexagonal close-packed AlN), Cr₂N, (CrAl)₂N) and Me-DLC (Si-DLC and Cr-DLC) coatings were prepared using a closed field unbalanced magnetron ...

Friction occurring between the crank journal and main bearings accounts for a large share of mechanical losses automotive engines. The effects higher in-cylinder pressures narrower have raised specific load applied to bearings, making it essential secure sufficient seizure resistance as well. For purpose meeting both requirements, we endeavored reduce friction improve by applying diamond-like c...