Introduction Direct pulp capping (DPC) is a treatment for maintaining pulp vitality and its biological function. Ideally, pulp capping agents are expected to induce pulp cells to form hard tissue. This in vitro study assessed the cytotoxicity and genotoxicity of three vital pulp capping (VPC) agents naming Biodentine (Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (ProRoo...

Aim The aim of this study was to evaluate the cytotoxicity effects of experimental gypsum-based biomaterial prepared with various concentrations of chitosan (Gyp-CHT). Materials and Methods The study was performed using cell viability assay for mitochondrial dehydrogenase activity in stem cells from human exfoliated deciduous teeth (SHED), after 1, 2, and 3 days of exposure to the biomaterial...

objective: bioactive glass is often used as a filler material for repair of dental bone defects. in different studies osteogenic potential of this material was proved, but its dentinogenesis property is in doubt. the purpose of this study was to evaluate the histological pulp responses of calcium hydroxide and bioactive glass placed directly on exposed pulp tissues. materials and methods: twent...

OBJECTIVE The purpose of this study was to investigate the pulpal response of dogs' teeth after pulpotomy and direct pulp protection with MTA Angelus, ProRoot, Portland cement and white Portland cement. STUDY DESIGN Seventy-six teeth were treated with these materials. One hundred twenty days after treatment, the animals were sacrificed and the specimens removed and prepared for histological a...

The aim of this study was to observe the histopathological pulp response following direct pulp capping of mechanically exposed teeth in rats with a composite of beta-tricalcium phosphate-hydroxyapatite bioceramic (BC) and poly (glycolic)-poly (lactic acid) (PLGA) material or a calcium hydroxide [Ca(OH)2] material, compared to BC alone and a negative control of water. Pulp of the maxillary molar...

introduction: the aim of the present investigation was to compare the efficacy of mineral trioxide aggregate (mta) and 0.2% chlorhexidine (chx) mixture to pure mta, as a pulp capping material. methods and materials: the pulp of 24 lateral incisors and canines from four dogs were exposed and capped either with mta or mta+0.2% chx. after 2 months the animals were sacrificed and the teeth were pre...