BACKGROUND The role of surgical therapy in gastric cancer patients with distant metastases remains controversial. This retrospective analysis was performed to identify whether gastric cancer patients with distant metastases might benefit from surgery. PATIENTS AND METHODS A total of 5185 patients from the SEER database who were initially diagnosed with histologically confirmed gastric cancer ...

OBJECTIVE Because the detection of the primary tumour is of importance to optimize the patient's management and allows a targeted therapy, the performance of hybrid positron emission tomography-computed tomography (PET/CT) using fluorodeoxyglucose (FDG) in the detection of primary tumors and unrecognized metastases with cervical lymph node metastases were evaluated in a retrospective study. M...

BACKGROUND We aimed to evaluate the clinical significance of microvessel density (MVD), lymphatic vessel density (LVD), and cancer-associated fibroblasts (CAFs) in relation to tumor location in advanced colorectal cancer (CRC). METHODS Using immunohistochemistry, we examined 181 advanced CRC patients for CD31 and D2-40 to measure MVD and LVD, respectively, α-smooth muscle actin (SMA) and desm...

Only 1% - 12% of patients with lung cancer develop cutaneous metastases. While adenocarcinoma is incredibly common, it rare for a manifestation the disease to be initial presenting complaint. Skin manifestations can difficult identify and appear deceptively benign, leading delays in diagnosis treatment. ALK+ specifically has an increased frequency distant lymph node involvement lymphangitic car...

Background: Determining the stage of non-small-cell lung cancer often requires multiple preoperative tests and invasive procedures. Whole body positron-emission tomography (PET) may simplify and improve the evaluation of patients with this tumor. Methods: We prospectively compared the ability of a standard approach to staging (computed tomography (CT), ultrasonography, bone scanning, and, when ...