Fungicides are important tools for managing diseases in many crops. Unlike insecticides and some herbicides which kill established insects or weeds, fungicides are most commonly applied to protect healthy plants from infection. To be effective, fungicides must be applied before infections become established and in a sufficient spray volume to achieve thorough coverage of the plant or treated ar...

An efficient and one-pot procedure is described for the synthesis of a variety derivatives 1,2-dihydrobenzo[f]chromen-3-ones 3,4-dihydrochromen-2-ones under solvent-free conditions via pseudo-four-component domino reaction acetic anhydride, aryl aldehydes, glycine-based dithiocarbamates, phenols/naphthols in presence l-proline H4[Si(W3O10)4].xH2O as green catalysts. All products were made strat...

Binuclear dithiocarbamate complexes of Ru(III) are promising candidates in the search for outstanding metal-based anticancer agents. While different dithiocarbamates have shown ligand-dependent cytotoxicity homoleptic binuclear complexes, properties heteroleptic analogues with (DTC) ligands yet to be explored. We herein propose introduction as tunable features development improved ruthenium-bas...

Previously published reports indicate that serum copper levels are elevated in patients with prostate cancer and that increased copper uptake can be used as a means to image prostate tumors. It is unclear, however, to what extent copper is required for prostate cancer cell function as we observed only modest effects of chelation strategies on the growth of these cells in vitro. With the goal of...

The thermal decomposition of Zn(II), Cd(II) and Hg(II) complexes of N-ethyl-N-phenyl and N-butyl-N-phenyl dithiocarbamates have been studied using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The products of the decomposition, at two different temperatures, were further characterized by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy ...

The zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1) is inhibited by several classes of zinc-binders (sulfonamides, sulfamates, and sulfamides) as well as by compounds which do not interact with the metal ion (phenols, polyamines and coumarins). Here we report a new class of potent CA inhibitors which bind the zinc ion: the dithiocarbamates (DTCs). They coordinate to the zinc ion from the enzyme...

Ethylbutylthiourea (EBTU) is an accelerator used in the production of chloroprene (neoprene) rubber. EBTU occurs in a mixture with diethylthiourea (DETU) and dibutylthiourea (DBTU) in the accelerator. An analytical method originally developed for analysis of zinc dithiocarbamates in rubber has been used to analyse EBTU, DETU and DBTU in a knee brace responsible for an allergic contact dermatiti...