Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated cardiomyopathy is the second most common cardiac disease and is most prevalent in the Irish Wolfhound, Doberman Pinscher and Newfoundla...

We report the first documented case of Bartonella washoensis bacteremia in a dog with mitral valve endocarditis. B. washoensis was isolated in 1995 from a human patient with cardiac disease. The main reservoir species appears to be ground squirrels (Spermophilus beecheyi) in the western United States. Based on echocardiographic findings, a diagnosis of infective vegetative valvular mitral endoc...

One-year-old Female Neutered Doberman Pincher weighing 32kg presented with a chronic non-healing wound on her tail stump that had an improper tail docking at Day two by the breeder. The owner reported that the dog had the wound all along and that she hoped it would heal with time. Many types of treatment and different wound management modalities were tried since the dog was eight weeks old at t...

BACKGROUND Dilated cardiomyopathy (DCM) is the most common cardiac disease in large breed dogs and is inherited in Doberman Pinschers with a high prevalence (58%). OBJECTIVE The European Society for Veterinary Cardiology convened a task force to formulate screening guidelines for DCM in Dobermans. RECOMMENDATIONS Screening for occult DCM in Dobermans should start at three years of age and u...

BACKGROUND Dilated cardiomyopathy (DCM) is the most common heart disease in Doberman Pinschers. MicroRNAs (miRNAs) are short non-coding RNAs playing important roles in gene regulation. Different miRNA expression patterns have been described for DCM in humans and might represent potential diagnostic markers. There are no studies investigating miRNA expression profiles in canine DCM. The aims of ...

BACKGROUND The dynamic component of disc-associated cervical spondylomyelopathy (DA-CSM) currently is evaluated using traction magnetic resonance imaging (MRI), which does not assess changes in flexion and extension of the cervical vertebral column. In humans with cervical spondylotic myelopathy, kinematic MRI is used to identify dynamic compressions. HYPOTHESIS/OBJECTIVES To evaluate the fea...

Paciente canino, fêmea da raça Pinscher com 7 anos de idade, histórico vômito e engasgos há 10 dias. Para fins complementação diagnóstica foram realizados exames radiografia simples esofagograma, onde foi observado um padrão alveolar em topografia lobo médio direito porção cranial do esquerdo sinais dilatação por conteúdo radiopacidade ar esôfago, promovendo desvio ventral traquéia.

BACKGROUND Occult (asymptomatic) dilated cardiomyopathy (ODCM) is highly prevalent in Doberman Pinschers. HYPOTHESIS/OBJECTIVES Assess ability of NT-proBNP assay to detect ODCM and predict death. ANIMALS 155 asymptomatic Dobermans presenting for ODCM screening. METHODS Echocardiography, 24-hour Holter, and NT-proBNP assay were performed prospectively. Diagnosis was based on increased left...

Cervical spondylomyelopathy (CSM) or wobbler syndrome is arguably the most common disease of the cervical spine of large and giant breed dogs. Data from the Veterinary Medical Database indicates a prevalence of CSM in Doberman Pinschers of 5.5%, and 4.2% in Great Danes (which may be an underestimate of its prevalence). In most reports, these two breeds account for 60-70% of the cases. CSM is al...

Levothyroxine administration has been suggested to be an effective treatment for canine von Willebrand disease (vWd), but evidence supporting this treatment is lacking. Effects of levothyroxine administration were evaluated in 8 euthyroid Doberman Pinschers with plasma von Willebrand factor (vWf) concentrations < 15%, characteristic of type 1 vWd. Levothyroxine (0.04 mg/kg PO q12h) and placebo ...