An enzymatic method for synthesizing various -D-glutamyl compounds efficiently and stereospecifically involving bacterial -glutamyltranspeptidase (EC 2.3.2.2) with D-glutamine as a -glutamyl donor was developed. With D-glutamine as a -glutamyl donor instead of L-glutamine in -glutamyltaurine synthesis, byproducts such as -glutamylglutamine and -glutamyl-glutamyltaurine were not synthesized and ...

Hot exciton materials have the potential to improve quantum efficiency of organic light-emitting diodes (OLEDs) by promoting high reversed intersystem crossing (hRISC) between a high-lying triplet (Tn, n ≥ 2) and radiative singlet (Sm). In recent years, donor–acceptor–donor (D–A–D) molecular systems shown great promise in its ability enhance hRISC process under certain conditions. However, stra...

Side chains are the necessary components for solution-processable semiconductors and exert significant influence on charge transport. In this work, a series of acceptor–donor–acceptor (A–D–A) small molecules (C1–C8) based...

The title donor, ethyl 2-acetamido-4,6-di-O-benzyl-2,3-N,O-carbonyl-2-deoxy-1-thio-beta-D-glycopyranoside, is shown to be an excellent glycosyl donor giving immediate and efficient access to variant GlcNAc-containing oligosaccharides.

Two D–A type polymers based on the gTDPP as acceptor and gTVT gTBTT donor have been developed. The unit affects backbone curvature aggregation properties of mixed conductors, regulating their performance in OECTs.

BACKGROUND Infection with cytomegalovirus (CMV) remains a potentially serious complication in transplant patients. In this study we explored the risk factors for CMV infection in the 12 months following a solid organ transplantation (n = 242) in patients monitored for CMV infection from 2004 to 2007. METHODS CMV infection was defined as 2 consecutive quantifiable CMV-polymerase chain reaction...

As fluorescence bioimaging has increased in popularity, there have been numerous reports on designing organic fluorophores with desirable properties amenable to perform this task, specifically emission the near-infrared II (NIR-II) region. One such strategy is utilize donor−π–acceptor−π–donor approach (D−π–A−π–D), as allows for control of photophysical resulting through modulation highest occup...

Langerhans cells (LC) and other antigen-presenting cells are believed to be critical in initiating graft versus host responses that influence the outcome of allogeneic hematopoietic stem cell transplantation. However, their fate in humans is poorly understood. We have sought to define the effect of conditioning regimes and graft versus host disease (GVHD) on the survival of recipient LC and rec...

Mixed hematopoietic chimerism is a state in which bone marrow hematopoietic stem cells from two genetically different animals coexist. We investigated whether mixed hematopoietic chimerism, resulting from the transplantation of host and donor bone marrow into a lethally irradiated rat, would confer donor-specific tolerance to lung allografts. Recipient rats (Fisher or or Wistar Furth [WF]) were...