The peroxide response-inducible genes ahpCF, dps, and katB in the obligate anaerobe Bacteroides fragilis are controlled by the redox-sensitive transcriptional activator OxyR. This is the first functional oxidative stress regulator identified and characterized in anaerobic bacteria. oxyR and dps were found to be divergently transcribed, with an overlap in their respective promoter regulatory reg...

Nutrients and other bioactive constituents of foods may interact with each other and the surrounding food matrix in complex ways. Therefore, associations between single nutrients and chronic disease may be difficult to identify and interpret, but when dietary patterns (DPs) are examined the combination of many food factors will be considered. An explorative literature search of published review...

Intradermal adipose tissue plays an essential role for hair follicles (HFs) regeneration by regulating hair cycles. However, the effect of reconstruction of HFs and the involvement of adipose-related cells are poorly understood. We investigated assembly strategies for the interactions of dermal papilla (DP) cells with adipose-derived stem cells (ASCs) in promoting hair formation. DP cells lose ...

The transition from adolescence to adulthood is a unique period during which lifelong dietary habits are shaped. Dietary patterns (DPs) among young adults attending college have not been adequately described, and associations between DPs and indicators of disease risk are not well understood in this age group. Dietary data were collected from undergraduates participating in the Tufts Longitudin...

We develop a stochastic mean-value method for the derivation of delay asymptotics in Processor-Sharing (PS) type systems with heavy-tailed service requirements. In order to demonstrate the strength of the approach, we apply the method to obtain the sojourn time asymptotics for a multi-class G/G/1 queue operating under the Discriminatory Processor-Sharing (DPS) discipline. Besides interesting fr...

An Escherichia coli O157:H7 dps::nptI mutant (FRIK 47991) was generated, and its survival was compared to that of the parent in HCl (synthetic gastric fluid, pH 1.8) and hydrogen peroxide (15 mM) challenges. The survival of the mutant in log phase (5-h culture) was significantly impaired (4-log(10)-CFU/ml reduction) compared to that of the parent strain (ca. 1.0-log(10)-CFU/ml reduction) after ...

This study was undertaken to determine the rates of sterol synthesis and uptake in the major organs of the female rat in vivo. At the mid-dark phase of the light cycle, control animals, animals in which hepatic sterol synthesis had been selectively inhibited by chylomicron infusion and animals in which the small intestine and liver had been surgically removed, were administered [(3)H]water, and...

Genitive of negation (GN) in Russian is a phenomenon in which an argument that bears structural Case in an affirmative sentence can surface bearing Genitive Case (GEN) in the corresponding negative sentence, as shown in (1). GN occurs only on Theme arguments, as shown in (2-4), and GN marked DPs refer to non-presupposed entities, whereas their structural Case-marked counterparts refer to presup...

Genetic studies and differing population trends support the separation of Steller sea lions (Eumetopias jubatus) into a western distinct population segment (WDPS) and an eastern DPS (EDPS) with the dividing line between populations at 144° W. Despite little exchange for thousands of years, the gap between the breeding ranges narrowed during the past 15-30 years with the formation of new rookeri...

This paper is concerned with algorithms for the efficient parallel solution of sparse, symmetric n × n linear systems via direct factorization, which eliminate groups of variables in stages. The algorithms make use of nested dissection to recursively cut data into pieces, producing orderings for direct elimination of the variables, so to reduce the storage and arithmetic requirements. Parallel ...