OBJECTIVE To assess whether monitoring sedation status using bispectral index (BIS) as an adjunct to clinical evaluation was associated with a reduction in the total amount of sedative drug used in a 12 h period. DESIGN Prospective randomized controlled clinical trial. SETTING Tertiary care neurocritical care unit. PATIENTS Sixty-seven mechanically ventilated adult patients receiving cont...

The astronomical site parameters for the Magdalena Ridge Observatory (MRO) are being studied from numerous aspects including meteorological, environmental, seismic and sky quality (e.g. “seeing”, cloud cover). Results to date indicate that MRO is an excellent site for astronomical observing. Seeing measurements of less that 1 arc second in the optical are routinely obtained. Seismic conditions ...

According to the authors, breast augmentation can be safely performed with the use of well-monitored sedation anesthesia. They credit this method with a brief recovery period, fast return to normal activity, minimal discomfort, and more safety and convenience than general anesthesia.

Less than one third of patients who suffer from major depressive disorder (MDD) report remission following antidepressant treatments requiring more diverse treatment approaches. Augmentation of second generation antipsychotics (SGAs) has been increasingly recognized as an important treatment option. The authors have previously provided a comprehensive review of SGAs for the treatment of MDD in ...

D eep learning methods are used on spectroscopic data to predict drug content in tablets from near infrared (NIR) spectra. Using convolutional neural networks (CNNs), features are extracted from the spectroscopic data. Extended multiplicative scatter correction (EMSC) and a novel spectral data augmentation method are benchmarked as preprocessing steps. The learned models perform better or on pa...

background and aims. autogenous onlay bone grafting is a common procedure for alveolar ridge augmentation. it has been suggested that the amount of healed bone after this technique would be significantly less than the initial quantity. the aim of this study was to determine the relationship between the various parameters influencing the outcome of ridge augmentation procedures. materials and me...

Nitroprusside was used to reduce afterload in 13 patients with isolated, severe aortic regurgitation. The drug significantly lowered mean aortic pressure, pulse pressure, left ventricular end-diastolic pressure and left ventricular volume. Total ventricular, or angiographic, cardiac index was generally unaffected, but forward cardiac index was improved significantly in 8 of 13 patients. Augment...