نتایج جستجو برای: drug combinations

تعداد نتایج: 659226  

2011
Xing-Ming Zhao Murat Iskar Georg Zeller Michael Kuhn Vera van Noort Peer Bork

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach to predict drug combinations by integrating molecular and pharmacological data. Specifically, drug...

2018
Warren Ladiges Denny Liggitt

Aging is a complex multifactorial process, meaning that multiple pathways need to be targeted to effectively prevent or slow aging [1]. A number of molecular pathways are well known for influencing aging, but only a few have been successfully targeted with individual drugs, and these drugs do not individually target all aging pathways. However, combinations of these drugs might have the potenti...

Journal: :Journal of Postgenomics Drug & Biomarker Development 2015

Journal: :Annual Review of Pharmacology and Toxicology 2019

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