Although liver dysfunction is not considered the main organ pathology or prognostic factor in patients with Systemic Lupus Erythematosus (SLE), it is not uncommon during the course of SLE. Liver complications in patients with SLE may be caused by lupus hepatitis (SLE-related hepatitis); autoimmune liver diseases, such as Autoimmune Hepatitis (AIH) and Primary Biliary Cirrhosis (PBC); viral hepa...

prison inmates are among the high risk population for dangerous infections such hiv, hbv, hcv and other contagious diseases. in spit of many data about the prevalence and risk factors for blood born diseases among prisoners in the world, such data are spares from iran. the aim of this study was to determine the prevalence and associated risk factors for hiv, hbv, hcv and hdv infections among a ...

BACKGROUND The long term outcome of drug related liver disease is unknown. AIMS To study the natural history of histologically proved drug induced hepatotoxicity. METHODS 110 patients with liver biopsies coded either as drug induced liver disease or hepatitis/cholestasis of unknown aetiology were identified from hospital records 1978-1996. Review of case notes and histology identified 44 pa...

injection drug use has been the most growing rout of drug abuse in iran in the past decade and it has been responsible for the transmission of hiv virus in more than two third of cases. the aim of the present study was to determine the prevalence of hiv and hepatitis b in a group of idu cadavers and to compare the results to a group of cadavers of the normal population. in a case-control study ...

background and purpose: hepatitis b is a major health problem around the globe the prevalence of which varies depending on the region and study. in this study, we aimed to determine the epidemiology and prevalence rates of hepatitis b in fasa, iran. methods: this descriptive, cross-sectional study was performed using medical records of all the hepatitis b patients referring to fasa health cente...

A 64-year-old man with no past medical history presented with abnormally elevated liver enzymes 1 year after developing a diffuse rash thought to be related to eating large quantities of raw cashew nuts. Liver biopsy was performed, which revealed features concerning for drug- or toxin-induced autoimmune hepatitis. The patient began treatment with azathioprine and prednisone, and liver enzymes n...

We report a case of methimazole-induced acute hepatic failure, which occurred 17 weeks after initiation of the drug in a 43-year-old man with hyperthyroidism and hepatitis B surface antigenemia. Postmortem needle autopsy of the liver revealed an established micronodular cirrhosis secondary to hepatitis B with moderate septal/portal inflammation, marked cholestasis and scattered acidophilic bodi...

PURPOSE We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. METHODS Case report. RESULTS A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolve...