introduction: multi-drug resistant (mdr) p. aeruginosa is constantly increasing and causing severe issues in combatting widely spread health problems. the aim of this study was to assess colistin susceptibility in mdr p. aeruginosa isolates obtained from different infection sites. methods: ninety clinical isolates of p. aeruginosa were collected from different hospitals of the tabriz university...

Antibacterial nanoagents with broad-spectrum antibacterial activities have emerged as an evolution of antibiotics. However, their bacteria-capturing capability and bacteria-killing efficiency remain insufficient for commercial implementation. Inspired by the hunting behavior spiders, here, a novel spiderweb-like nanoagent based on silver-adenine nanowires is designed to achieve high-efficiency ...

Background: Blood stream infection is one of the main causes of morbidity and mortality in patients with cancer. The purpose of this study was to evaluate the prevalence of aerobic and anaerobic-bacteremia in hospital inpatients with cancer and to determine the antibiotic resistance profile in isolated organisms in Kerman, southeast Iran. Methods: Total of 240 blood cultures from 136 patients w...

In the mid-50s of last century, reports began to appear about ineffectiveness sulfonamides and antibiotics in bacterial infections. And soon widespread spread numerous strains antibiotic-resistant microorganisms was noted. The fight against drug-resistant bacteria is carried out several directions: obtaining new chemotherapeutic drugs, chemical modification known antibiotics, or use inhibitors ...

Multi-drug resistant bacteria are a public health problem associated with high morbidity and mortality globally. This increasing drug resistance has been linked to gene exchange between bacteria. Integrons systems known play significant role in the acquisition dissemination of antimicrobial genes especially Gram negative Hence, this study aims evaluate integrons members Enterobacteriaceae obtai...

Some drug management systems have been established in Japanese hospitals to reduce medical costs and regulate drug usage. Among the many available prescription drugs, antimicrobials should be given special attention because their inappropriate use often leads to sudden outbreaks of resistant bacteria. As drug specialists, pharmacists should monitor the use of all drugs, particularly antimicrobi...

although the conventional therapies have obviously improved the conditions of patients with cancer, some mechanisms of resistance have led scientists to use alternative agents that can penetrate in most solid tumors. furthermore, the success of cancer therapies depends on limiting the uptake of toxins to normal tissues and their selectivity to malignant cells. the involvement of natural and gen...

materials and methods lactic acid bacteria isolated from spoiled fruits and vegetables and grown in mrs medium were screened against multi-drug-resistant candida albicans, klebsiella pneumoniae, pseudomonas aeruginosa, escherichia coli, and enterococcus fecalis. results fifty-four lactic acid bacteria were isolated from spoiled fruits and vegetables, of which 11 gram-positive and catalase-negat...