During agitated drying and mixing processes, particle beds are exposed to shear deformation. This leads to particle attrition, the extent of which is dependent on the prevailing stresses and strains in the bed. The distributions of shear stresses and strain rates within the bed are highly non-uniform, requiring attention to localised conditions. Therefore a narrow angular sector of the bed is d...

The aim of the present study was to investigate the influence of process shear stressors on the stability of a model monoclonal antibody, trastuzumab. Trastuzumab, at concentrations of 0.4-4.0 mg/mL, was subjected to sonication, freeze-thaw, lyophilisation, spray drying and was encapsulated into micro- and nanoparticles. The stressed samples were analysed for structural integrity by gel electro...

In this study, effect of drying method and time temperature regime of extraction on quality of mango kernel lipid was evaluated. Hot air drying required drying of seeds for long intervals and exposure to higher temperature, where as microwave drying was found to be quick due to heating induced at the molecular level. The drying time under optimized conditions for microwave was reduced by 34 fol...

purpose: to evaluate the effect of vertical prism induced stress on binocular visual evoked potentials. methods: using checkerboard stimulus patterns in two spatial frequencies (sfs) of 0.48 cpd as a low sf and 2.18 cpd as a moderate sf reversing with temporal frequency of 4 hz, the effect of increasing visual stress using vertical prisms of 0, 1, 2 and 3 prism diopters on binocular visual evok...

in this research, a novel method to decrease micro-residual stresses of fibrous composites by adding carbon nanotubes (cnts) is proposed in detail. the negative coefficient of thermal expansion and the high young’s modulus of cnts can be utilized to counterbalance the process induced residual stresses in composites. to this end, first, the effects of adding cnts to the matrix of fibrous composi...

This study shows that dehydration induces imbalanced metabolism before loss of membrane integrity in desiccation-sensitive germinated radicles. Using a photoacoustic detection system, responses of CO(2) emission and fermentation to drying were analyzed non-invasively in desiccation-tolerant and -intolerant radicles of cucumber (Cucumis sativa) and pea (Pisum sativum). Survival after drying and ...

In the present study, a suitable drying method was developed for citrus press cakes (CPCs), which are produced as a by-product in citrus juice plants, and the protective effect of methanol extract of CPCs prepared by far-infrared radiation (FIR) drying against H(2)O(2)-induced DNA damage was evaluated versus that of freeze-dried CPCs. Methanol extract of FIR-dried CPCs exhibited comparatively g...