BACKGROUND The diagnosis of celiac disease is dependent on the quality of biopsy specimens obtained at EGD. Endoscopists may obtain a single- or double-biopsy specimen with each pass of the forceps. OBJECTIVE To compare the quality of biopsy specimens obtained with the single-biopsy and double-biopsy techniques. DESIGN Prospective cohort study. SETTING U.S. tertiary-care university hospit...

background: blood group antigen binding adhesin ( baba2 ) , is essential for attachment of helicobacter pylori (h. pylori) to the epithelial cell layer and is the most important adhesin of h. pylori . the prevalence rate of the baba2 gene varies in different geographic areas. the aim of this study is to determine the frequency of the baba2 gene in patients with different clinical outcomes. mate...

Fifty nine patients seropositive for human immunodeficiency virus (HIV) and diarrhoea and 20 with weight loss were investigated for microsporidiosis using light and electron microscopical examination of duodenal and jejunal biopsy specimens. Eight cases of microsporidiosis were found, in five of whom it was the sole pathogen. In all eight cases the organism was identified at light microscopy wi...

OBJECTIVE To investigate whether there is an association between chronic peripheral neuropathy and coeliac disease. METHODS The cause of chronic peripheral neuropathy was first investigated in a group of 478 patients. Published reports were then examined systematically for an association between chronic peripheral neuropathy and coeliac disease. Cases were divided into two groups: group A, po...

CONTEXT Intestinal parasites induce detectable histopathological changes, which have been studied in groups with known diagnosis of parasitic disease. There is no available study with a larger base without previous diagnosis. OBJECTIVE To describe clinical and histopathological findings of parasitosis diagnosed by endoscopic biopsy in patients submitted to upper digestive endoscopy. METHODS...

Gastrointestinal tract lymphangiomas are extremely rarely seen. Here, we present the first case of lymphangioma of the duodenal bulb diagnosed with a deep bite on a bite endoscopic biopsy and treated with polypectomy.

BACKGROUND Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for comparing duodenal histology before and after introducing a gluten-free diet is not yet established. Our aim was to evaluate a novel criterion to compare duodenal histology in c...

At operations on 150 patients the duodenal bulb was examined for local features which predispose it to peptic ulceration. A surgeon now has the opportunity to study the duodenum in its natural state and normal situation in both healthy and ulcerated conditions. When gastroenterostomy or partial gastrectomy were routinely used for the cure of duodenal ulcers, the bulb was either left unopened or...