Pectus excavatum is the most common congenital deformity of the anterior chest wall, in which an abnormal formation of the rib cage gives the chest a caved-in or sunken appearance. Today, the surgical correction of this deformity is carried out in children and adults through Nuss technic, which consists in the placement of a prosthetic bar under the sternum and over the ribs. Although this tech...

Background: The maintenance of deformity in the ankle and hindfoot after correction of knee deformity following kneearthroplasty may cause abnormal tension in the knee and patient dissatisfaction. The aim of this study was to determinethe effect of knee arthroplasty on the hindfoot alignment in patients with severe genu varum and valgum.Methods: A total of 84 patients with pri...

Varus and valgus deformities of the foot in cerebral palsy (1982) Another in our series of commentaries on notable papers from the DMCN archives. Deformities of the foot and ankle are common among patients with cerebral palsy. Equinus due to contracture of the gastrocne-mius-soleus muscle is the most common: it has been estimated that some 20 to 25 per cent of all children with cerebral palsy w...

Survivors of infantile meningococcal septicaemia often develop progressive skeletal deformity as a result of physeal damage at many sites, particularly in the lower limb. Distal tibial physeal arrest typically occurs with sparing of the distal fibular physis leading to a rapidly progressive varus deformity. There have been reports of isolated cases of this deformity, but to our knowledge there ...

BACKGROUND A triad of deformities-thoracolumbar scoliosis, pelvic obliquity, and femoral head (hip) subluxation/dislocation-occurs frequently in non-ambulatory neuromuscular patients, but their close inter-relationship is infrequently appreciated or quantified. We propose a deformity documentation approach to assess each component simultaneously. METHODS The documentation assesses each compon...

Methods The following were used in the evaluation: Bad Sobernheim Stress Questionnaire (Brace and Deformity), Trunk Appearance Perception Scale (TAPS), and Knee – Feet Perception Scale (KFPS). The BSSQ Brace estimates the stress scoliosis patients have whilst wearing brace, the BSSQ Deformity estimates the stress involved with body deformation. Minimal points number equals 0 (the greatest stres...

STUDY DESIGN Descriptive study of the Scoliosis Research Society (SRS) Classification for Adult Spinal Deformity using interobserver reliability measures for validation of the system. OBJECTIVES To propose and validate a classification system for adult spinal deformity that will have utility in reporting on treatment options and outcomes for affected adults. SUMMARY OF BACKGROUND DATA Class...

In the simplest view of transcriptional regulation, the expression of a gene is turned on or off by changes in the concentration of a transcription factor (TF). We use recent data on noise levels in gene expression to show that it should be possible to transmit much more than just one regulatory bit. Realizing this optimal information capacity would require that the dynamic range of TF concentr...

Total hip arthroplasty (THA) in proximal femoral deformity represents a relatively uncommon challenge. Proximal femoral deformity is classified depending on the etiology and location and geometry of the deformity. Classification by etiology includes developmental processes, previous trauma, or previous surgery (osteotomy or THA). The latter, previous surgery, is the most common cause of femoral...