Dyspepsia is a digestive syndrome distinct from (although frequently overlapping with) gastro-oesophageal reflux disease (GORD) and irritable bowel syndrome (IBS), which is characterised by various combinations of painful and non-painful symptoms arising from the epigastrium. Dyspepsia can be secondary to a variety of diseases, but in most instances it is idiopathic. Helicobacter pylori infecti...

BACKGROUND To investigate any possible relationship between serum leptin level and H.pylori infection in dyspeptic Iranian adults. METHODS A total of 153 dyspeptic patients referring to Firoozgar hospital for esophagogastroduodenoscopywere enrolled in the study. Serum leptin level was measuredbefore endoscopy, after overnight fasting. Two biopsy specimens weretaken from antrum for each patien...

BACKGROUND Various international guidelines recommend the use of non-endoscopic tests [such as urea breath test (UBT)] for the evaluation of dyspeptic patients, unless endoscopy is clinically indicated. AIM To assess adherence with guidelines for UBT referrals among primary care doctors in Israel. METHODS Patients referred by primary care doctors to an open-access UBT service were included ...

OBJECTIVE Although gastroesophageal reflux disease (GERD), a very common disorder worldwide, is considered to be a lifestyle disease, the pathogenic role of lifestyle factors and consequently the efficacy of lifestyle interventions, remains controversial. Lifestyle factors associated with GERD and the beneficial effect of specific recommended lifestyle interventions in the primary care setting ...

BACKGROUND Helicobacter pylori (H. pylori) colonizes in half of the population of developed and nearly all inhabitants of developing countries. The infection is characterized by gastritis but can present more complicated disease states. We intended to report prevalence of H. pylori infection by histopathology and presence of gastritis, activity, atrophy and intestinal metaplasia in dyspeptic pa...

In order to investigate the therapeutic potential of acupuncture on patients with functional dyspepsia (FD), patients were randomized to receive acupuncture at classic acupoints with manipulations (treatment group) versus acupuncture at nonacupoints without manipulation (control group) once every other day, three times a week, for one month and were followed up for three months. The primary out...

BACKGROUND Chronic atrophic gastritis (CAG) is a precursor of the intestinal type of gastric cancer, the second leading cause of cancer-related death worldwide. GastroPanel is a recently marketed serological kit for the non-invasive diagnosis of CAG, defined by some authors "even more reliable than biopsy histology". The goal of this study was 1) to evaluate the agreement between the serum gast...

The main purpose of the study is to determine resistance pattern of bacterial isolates to selected antibiotics among 88 dyspeptic patients in Iran. Frequency of infection among these patients have been evaluated among dyspeptic patients old (45 boys and 43 girls, aged 5-18 years) from 2016 to 2017.Eighty-eight patients with gastroduodenal disorders were included in the study. Urease test modifi...

gastroesophageal reflux disease (gerd) is the main known etiological factor for barrett’s esophagus (be), and be is the precursor lesion of esophageal adenocarcinoma. the prevalence of be is reported mostly from gastroenterology centers and there are only a few reported cases from outpatients with dyspepsia. a large number of patients with gerd have degrees of dyspepsia. this study primarily ai...

The water drink test is a good tool to evoke dyspeptic symptoms. To what extent these symptoms are related to altered gastric distribution is not clear. Therefore, we determined gastric volumes after a drink test using SPECT. After a baseline scan 20 healthy volunteers (HV) and 18 patients with functional dyspepsia (FD) underwent a drink test (100 mL min(-1)) followed by five scans up to 2 h. D...