Enhanced cytogenetic damage by cyclophosphamide (CP) was observed when Ehrlich ascites tumor cells were exposed in vivo to nontoxic concentrations of caffeine. One h before i.p. injection of 5-bromodeoxyuridine adsorbed to activated charcoal Ehrlich ascites tumor-bearing mice treated i.p. with CP appear to have a dose-dependent increase in sister chromatid exchange rates and cell division delay...

When given by direct s.c. injection into the Ehrlich solid carcinoma 1 week after s.c. tumor transfer, viable crude spores of Clostridium perfringens type A (attenuated mutant strain LNG11 ATCC 29348) inhibited tumor growth and significantly prolonged the life span of male outbred Swiss mice. Under these conditions a concentrated sterile supernatant of a C. perfringens culture proved to be slig...

The phospholipides of Ehrlich ascites carcinoma of the mouse are capable of rapidly incorporating amino acids following in vivo or in vitro incubation of the cells with the labeled compounds. Glucose (0.005 M) stimulated the in vitro uptake of leucine and alanine by the phospholipides of the ascites cells. The amino acids appeared to be readily liberated by the phospholipides into the amino aci...

Two mouse ascites tumors, the Ehrlich carcinonm and the TM nmmniary carcinoma, have been established as permanent cell strains in tissue culture. Both cell strains have been carried by serial subcultivation through more than 60 passages during a 15-month period. The cell lines have been established and propagated in synthetic medium M 150, supplemented with a low level of calf serum. When inocu...

The phospholipides of Ehrlich ascites carcinoma of the mouse are capable of rapidly incorporating amino acids following in vivo or in vitro incubation of the cells with the labeled compounds. Glucose (0.005 M) stimulated the in vitro uptake of leucine and alanine by the phospholipides of the ascites cells. The amino acids appeared to be readily liberated by the phospholipides into the amino aci...

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantl...

The methanolic extracts of Indigofera aspalathoides (MEIA) and Wedelia calendulaceae (MEWC) were evaluated for their anticancer activity against Ehrlich Ascites Carcinoma (EAC) in Swiss albino mice. On day 1, the extract of Indigofera aspalathoides at a dose of 250 and 500 mg/kg body weight and the extract of Wedelia calendulaceae at a dose of 250 and 500 mg/kg body weight were administered ora...