We report a 61-year-old man with multiple colored skin papules with central crusts in an archiform and linear pattern on his forehead as well as verrucus and hyperkeratotic plaques with central perforation on hands. Histologic examination of the lesions demonstrated a narrow channel of epidermal perforation containing notrophils, basophilic debris and elastic fibers with eosinophilic degenerati...

Cutaneous malignant melanomas with histologic evidence of an associated nevus (N+) may have a different risk factor profile from that of melanomas without it (N-). To address this question, a case-only analysis of 932 people with cutaneous malignant melanoma was done to identify etiologic and other factors associated with N+ melanoma. Evidence of an associated nevus was found in 36% of melanoma...

Background Acquired elastotic hemangioma is a benign vascular proliferation that typically presents as an asymptomatic red plaque on a sun-exposed site of an adult. Material and Methods The PubMed database was used to search the following words: acquired, angioma, arm, basal, carcinoma, cell, elastosis, elastotic, exposed, forearm, hemangioma, solar, sun, and vascular. The relevant papers and r...

It may be useful to look at the risk patterns for developing a second primary malignancy after a first primary melanoma diagnosis in order to understand the etiology and mortality due to melanoma. In this volume, W.B. Grant has proposed the interesting hypothesis that solar UV radiation and smoking may be inversely associated with the development of melanoma through the presence of dermal or so...

Asians differ from Caucasians as photoageing tends to present with pigmentary changes as the main issue. Furthermore, with a higher epidermal melanin context, there is a greater risk of complications especially postinflammatory hyperpigmentation and such high epidermal melanin context also acts as a competing chromophobe for the underlying target. In this review article, recent advances in the ...

A 14-year-old girl was first seen with an 8-month history of an asymptomatic “rash” on her chin and a “wart” on her right hand. At physical examination, she had several pink papules coalescing into annular and arcuate plaques on the central aspect of her chin (Figure 1). She was also noted to have a single flesh-colored verrucous papule on her right palm, which was treated with liquid nitrogen ...

BACKGROUND Light chemical peels and microdermabrasion have enjoyed recent popularity for the treatment of mild photoaging. However, clinical improvement from these modalities is often minimal from both a patient's and physician's perspective. Erbium:YAG lasers have been effective in treating mild to moderate photoaging, but the need for either regional or general anesthesia, as well as the sign...