We investigated the effects of heterogeneous regions on dose deposition of very high-energy electrons (VHEE) using both Geant4 simulations and experiments performed at the CALIFES facility at CERN. Small air and acetal plastic (bone equivalent) cavities were embedded in a water phantom and irradiated with a 197 MeV electron beam. Experimentally determined transverse dose profiles were acquired ...

Monte Carlo water-equivalence study of two PRESAGE® formulations for proton beam dosimetry T Gorjiara, Z Kuncic, J Adamovics and C Baldock 2013 J. Phys.: Conf. Ser. 444 012090 PRESAGE® is a radiochromic solid dosimeter which shows promising potential for 3D proton beam dosimetry. Since an idea dosimeter should be water-equivalent, total depth dose distributions in two PRESAGE® formulations irra...

Gold nanoparticle assemblies possess diverse application potential, ranging from industrial nanotechnology to medical biotechnology. Because the structures and properties of assemblies are directly affected by the stabilization mechanism between the organic molecules serving as protecting ligands and the gold nanoparticle surface, it is crucial to find and investigate new stabilization mechanis...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background: in radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. metho...

Electron beams in Scanning Transmission Microscopes (STEMs) can be used as a tool to induce movement on nanoparticles. Employing classical-electrodynamics approach, it has been reported that the linear momentum transfer from STEM-beam electron metallic spherical nanoparticle either repulsive or attractive towards swift trajectory. This is qualitative agreement with experimental observations. Th...

We have experimentally confirmed sensitivity enhancement of a nanowire-based surface plasmon resonance (SPR) sensor structure. Gold nanowires with periods of 200 and 500 nm were fabricated, respectively, by electron-beam and interference lithography on a gold/SF10 substrate. Sensitivity enhancement was measured to be 44% compared with a conventional thin-film-based SPR structure for nanowires o...

This study investigated radiation dose variations in pre-clinical irradiation due to the photon beam energy and presence of tissue heterogeneity. Based on the same mouse computed tomography image dataset, three phantoms namely, heterogeneous, homogeneous and bone homogeneous were used. These phantoms were generated by overriding the relative electron density of no voxel (heterogeneous), all vox...

Background and Aims: Gold nanoparticles have potential applications in the areas of medicine, target drug delivery, cancer diagnosis and therapy, electronic, etc. Recently, biological system is considered as an environmental friendly method for synthesis of stable nanoparticles. Methods: We demonstrated a biological system for formation of stable gold nanoparticle by using Cupriavidus necator w...

Background: Normoxic type MAGICA gel dosimeters are established for dose quantification in three dimensions for radiotherapy. Objective(s): The ability of MAGICA polymer gel was assessed by experimental measurements method for studying the effect of gold nanoparticles (GNPs) in dose enhancement under the external 18MV radiotherapy practices. <...