Different weight percentages of ZrO2 (0, 3, 5, 7 and 10 wt%) incorporated electrospun PVDF-HFP nanocomposite polymer membranes (esCPMs) were prepared by electrospinning technique. They were activated by soaking in 1 M LiPF6 containing 1:1 volume ratio of EC : DMC (ethylene carbonate:dimethyl carbonate) to get electrospun nanocomposite polymer membrane electrolytes (esCPMEs). The influence of Zr...

*Correspondence: Claudia Merlini and Guilherme Mariz de Oliveira Barra, Department of Mechanical Engineering, Universidade Federal de Santa Catarina, Campus Universitário Trindade, Caixa Postal 476, Florianópolis, Santa Catarina 88040-900, Brazil e-mail: dra.claudiamerlini@ yahoo.com.br; [email protected] Electrically conductive polyaniline (PANI)-coated electrospun poly(vinylidene fluoride) (PVD...

Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases. Here we synthesize reactive macromers that contain protease-cleavable and fluorescent ...

Poly(L-lactide-co-ε-caprolactone) nanofibers with heparin incorporated were successfully fabricated by coaxial electrospinning. The morphologies of electrospun nanofibers were studied by scanning electron microscopy (SEM), and a significant decrease in fiber diameter was observed with increasing heparin concentration. The transmission electron microscopy (TEM) images indicated that coaxial elec...

The worldwide increase in the number of people suffering from diabetes has been the driving force for the development of glucose sensors. The recent past has devised various approaches to formulate glucose sensors using various nanostructure materials. This review presents a combined survey of these various approaches, with emphasis on the current progress in the use of electrospun nanofibers a...

The aim of this study was to investigate macrophage interactions with electrospun scaffolds and quantify the expression of key angiogenic growth factors in vitro. This study will further help in evaluating the potential of these electrospun constructs as vascular grafts for tissue repair and regeneration in situ. Human peripheral blood macrophages were seeded in serum free media on electrospun ...

The development of nanoscaled materials has deserved a remarkable interest for biomedical applications. Biological tissues are essentially composite materials with particular mechanical properties that should be carefully considered during the design of innovative biomedical scaffolds. Electrospun membranes are often found in medical applications due to its high specific surface which creates a...

Nowadays, polymer nanofibers have gained attention due to remarkable characteristics such as high porosity and large surface area to volume ratio. Among their fabrication methods, electrospinning technique has been attracted as a simple and reproducible approach. It is a versatile, simple and cost-effective technique for the production of continuous nanofibers with acceptable characteristics su...

This study was aimed at assessing the potential use of electrospun fibers as drug delivery vehicles with focus on the different diameters and drug contents to control drug release and polymer fiber degradation. A drug-loaded solvent-casting polymer film was made with an average thickness of 100 microm for comparative purposes. DSC analysis indicated that electrospun fibers had a lower T(g) but ...

Wound healing is a complex tissue regeneration process that promotes the growth of new tissue to provide the body with the necessary barrier from the outside environment. In the class of non-healing wounds, diabetic wounds, and ulcers, dressing materials that are available clinically (e.g., gels and creams) have demonstrated only a slow improvement with current available technologies. Among all...