conclusions results indicated that the present vaccination program is insufficient for immunity against measles in this area. the general population immunity was lower than the necessary level for the elimination of measles. therefore, sero-epidemiological studies are necessary to organize national programs for control and elimination of measles. results overall, 821 (91.2%) of the studied popu...

BACKGROUND Countries in the different stages of pre-elimination, elimination, and prevention of reintroduction are required to report the number of indigenous and imported malaria cases to the World Health Organization (WHO). However, these data have not been systematically analysed at the global level. OBJECTIVE For the period 2007 to 2013, we aimed to report on 1) the proportion of countrie...

Malignant gliomas are characterized by an intrinsic resistance to apoptosis. Increasing evidence suggests that this is a fundamental mechanism by which gliomas evade elimination when treated with both conventional and targeted therapies. In this review, we describe the multiple anti-apoptotic signals that have been demonstrated to be active in malignant gliomas. We describe the preclinical evid...

False sharing can be a source of signiicant overhead on shared-memory multiprocessors. Several program restructuring techniques to reduce false sharing have been proposed in past work. In this paper, we propose an approach for elimination of false sharing based solely on selection of runtime schedule parameters for parallel loops. This approach leads to more portable code since only the schedul...

We study two different techniques for the computation of a matrix inverse, the traditional approach based on Gaussian factorization and the Gauss-Jordan elimination alternative more suitable for parallel architectures. The target architecture is a current general-purpose multi-core processor (CPU) connected to a graphics processor (GPU). Parallelism is obtained from the use of libraries MKL (fo...

Preamble The Global Vaccine Action Plan 2012-2020, established the target of eliminating measles and rubella in at least 5 WHO Regions by 2020. The SAGE Working Group on Measles and Rubella has prepared revised guidance on how to monitor progress towards and verify elimination of measles and rubella to ensure alignment between the activities of different regions. This guidance, or framework, bu...

Prior to the widespread availability of antiretroviral therapy (ART), the desire to conceive among HIV-positive women was discouraged due to a high perinatal transmission risk [1]. The recent advancement in HIV therapy has transformed the conceptualization of the infection. In particular, highly effective prevention strategies have led to a near elimination of the pediatric HIV epidemic in the ...

Experience refines synaptic connectivity through neural activity-dependent regulation of transcription factors. Although activity-dependent regulation of transcription factors has been well described, it is unknown whether synaptic activity and local, dendritic regulation of the induced transcripts are necessary for mammalian synaptic plasticity in response to transcription factor activation. N...

Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance. Recently, however, there has been renewed interest in the role of MDA as an elimination tool. Following a 2013 Cochrane Review that focused on the quantitative effects of m...