In this study, microemulsions of the chiral surfactant polysodium N-undecenoyl-D-valinate (poly-D-SUV) was utilized for enantiomeric separation by investigating two approaches using polymeric chiral surfactant in microemulsion electrokinetic chromatography (MEEKC). In the first approach, poly-D-SUV was used as an emulsifier surfactant along with 1-butanol and n-heptane. Enantioseparation of ani...

A new optomechanical chiral resolution scheme for molecules possessing a permanent dipole moment is proposed. The approach involves the following molecular manipulation sequence: (i) alignment electromagnetic pulse, (ii) time-delayed orienting static electric field, and (iii) scattering from frictional surface. method offers various control parameters including pulse duration intensity, field s...

In chiral and non-chiral electrophoretic resolution of basic drugs, adsorption of analytes to negatively charged capillary wall could lead to poor repeatability of migration time and peak area. In addition, chiral resolutions of basic drugs are commonly performed in low pH buffers. Therefore, longer analysis time due to suppression of electroosmotic flow (EOF) is another dilemma. In this work t...

In this study molecular imprinting technology was employed to prepare a specific affinity sorbent for the resolution of Methylephedrine, a chiral drug. The molecularly imprinted polymer (MIP) was prepared by non-covalent molecular imprinting with either (+) or (-)-Methylephedrine ((R*,S*)-2-(methylamino)-1phenylpropan-1-ol) as the template. Methacrylic acid and ethylene glycol di-methacrylate w...