نتایج جستجو برای: enriched gene ontology
تعداد نتایج: 1222859 فیلتر نتایج به سال:
BACKGROUND The Gene Ontology (GO) (http://www.geneontology.org/) contains a set of terms for describing the activity and actions of gene products across all kingdoms of life. Each of these activities is executed in a location within a cell or in the vicinity of a cell. In order to capture this context, the GO includes a sub-ontology called the Cellular Component (CC) ontology (GO-CCO). The prim...
Iodine is the main ingredient produced by the thyroid hormone, which playa a central role in the metabolism and the immune system. The present study aims to evaluate the effects of feeding Artemia fransiscana enriched with potassium iodide on antioxidant and immune gene expression in zebra fish (Danio rerio). Zebra larvae with an average weight of 2±0.01 mg were randomly distributed into 4 trea...
aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research. background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...
The purpose of this study was to identify differentially expressed genes and analyze biological processes related to leukemia. A meta-analysis was performed using the Rank Product package of Gene Expression Omnibus datasets for leukemia. Next, Gene Ontology-enrichment analysis and pathway analysis were performed using the Gene Ontology website and Kyoto Encyclopedia of Genes and Genomes. A prot...
Abstract Background and Aims This study aimed to explore the possible role of plasma PBMCs circular RNA (circRNA) in systemic lupus erythematosus (SLE). Method Total was extracted from blood samples obtained 10 patients with SLE healthy controls subjected microarray analysis define profile circRNA expression. The quantitative reverse transcription-polymerase chain reaction amplification (qRT-PC...
YAP and TAZ are critical downstream effectors of the hippo signaling pathway, which play pivotal roles in controlling organ size maintaining tissue homeostasis. Although dysregulation YAP/TAZ has been linked to various human diseases their role dermal extracellular matrix (ECM) regulation remains largely unknown. Here, we describe mouse ECM maturation during early postnatal development We find ...
Abstract Background SCL/TAL1 interrupting locus (STIL) is associated with the progression of several tumors; however, biological role STIL in osteosarcoma remains poorly understood. Methods In this study, clinical significance was analyzed by gene chip data recorded public databases. expression silenced cell lines to observe effects on proliferation, apoptosis, invasion, and migration. Differen...
Hepatocellular carcinoma (HCC) poses a severe threat to human health. The NET-1 protein has been proved be strongly associated with HCC proliferation and metastasis in our previous study. Here, we established validated the siRNA nanoparticles system conduct targeted gene therapy of xenograft vivo aid sonodynamic therapy. Then, conducted label-free proteome mass spectrometry workflow analyze for...
Objective(s): Schwann cells (SCs) have a wide range of applications as seed cells in the treatment of nerve injury during transplantation. However, there has been no report yet on kinds of proteomics changes that occur in Schwann cells before and after peripheral nerve injury.Materials and Methods: Activated Schwann cells (ASCs) and normal Schwann cells (NSCs) were obtained from adult Wistar ra...
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