Myoclonus is a clinical sign characterized by brief, involuntary, jerky contraction or lapse of muscle group muscles, which can be associated with cerebral disorders, epileptic and drugs. Megestrol acetate (MGA) synthetic derivative progestin, has been widely used in practice for increasing appetite patients severe anorexia malignancies. We experienced 68-year-old female patient who myoclonus a...

With the burgeoning array of molecular tests available in the epilepsies, the clinician needs to know which tests to order for each patient. Epileptic encephalopathies are the most important clinical group for genetic testing with an increasing number of distinctive epilepsy syndromes being recognized. Identification of the causative mutation affects treatment as well as prognostic and genetic ...

The current classification of the epilepsies and epileptic syndromes is practical and useful in a majority of cases. However, the choice of its subdivisions was mainly derived from adult data, and its applicability is frequently problematic in early childhood. This article reviews some issues related to the classification of epilepsies in childhood and summarizes recent proposals that might imp...

The clinical evidences of variable epileptic propagation in occipital lobe epilepsy (OLE) have been demonstrated by several studies. However the exact localization of the epileptic focus sometimes represents a problem because of the rapid propagation to frontal, parietal, or temporal regions. Each white matter pathway close to the supposed initial focus can lead the propagation towards a specif...

Epilepsy is diagnosed when persisting cerebral dysfunction causes recurring epileptic seizures. Distinction between different epileptic syndromes requires a comprehensive clinical workup, including functional neuroimaging techniques. The most established techniques are single photon emission computer tomography (SPECT), mainly used to detect local blood flow changes during ictal activity, and p...

PURPOSE To assess the advantages of the 2001 ILAE proposed diagnostic scheme for classification of newborns with epileptic seizures over the 1989 ILAE classification. METHOD Clinical features, seizure semiology and duration, neurological evaluation, ictal and interictal EEG, brain imaging and outcome at the end of the neonatal period (44 weeks post-conceptional age) of 94 newborns with EEG co...

Epilepsy is a relatively frequent pathology in child populations, with an annual incidence rate ranging from 41 to 67 per 100 000 cases1-7. In the past decade, many important advances related to epilepsy have arisen. On one hand, new diagnostic methods (video electroencephalography monitoring, structural and/or functional neuroimaging, metabolic and genetic analysis, etc) facilitate the diagnos...

The International League Against Epilepsy (ILAE) made a major contribution when it established standardized classifications and terminology for epileptic seizures and syndromes. This provided a universal vocabulary that not only facilitated communication among clinicians, but also established a taxonomic foundation for performing quantitative clinical and basic research on epilepsy. Much, howev...

Quantitative measurements have indicated that heredity, cerebral damage, psycho-social aspects, ictal and inter-ictal phenomena and antiepileptic drugs may interfere in the cognitive dysfunction of epileptic patients. In the present study objective methods included immediate and late recall and recognition of pictures, Stroop test and auditory selection. Twenty patients with symptomatic localiz...