AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...

AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...

Background: Chlamydia (C.) trachomatis is an obligate intracellular gram-negative pathogen affecting over 600 million people worldwide with 92 million new cases occurring globally each year. Genital C. trachomatis infection has been recognized as the most common cause of pelvic inflammatory disease leading to severe tubal damage, ectopic pregnancy, hydrosalpinx and infertility. However, the mec...

Background: Lead (Pb) is one of the most important environmental pollutants that affect the male reproductive system. The aim of this study was to investigate the protective effect of green tea extract on lead-induced oxidative stress, apoptosis and morphometric changes in male mouse epididymis. Materials and Methods: Forty adult male mice were randomly divided into four groups (n= 10), as foll...

epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. here a case of 58-year-old female presented with left cheek swelling of one-year duration. ct scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. histological examin...

Mesenchymal Stem Cells Trigger Epithelial to Transition in the HT-29 Colorectal Cancer Cell Line

The respiratory tract contains numerous peptides secreted from special pulmonary epithelial cells whichare called endocrine cells. The function of neuroendocrine cells is modulated by amines. Serotonin has strong vasomotor and bronchomotor effects in the airway mucosa. The objective of this study was to determine presence and distribution of serotonin-positive endocrine cells in respiratory tra...

introduction to evaluate the expression patterns of cytokeratin (k) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether k13 could be used as a marker for conjunctival epithelium. methods: total rna was isolated from the human conjunctiva and central cornea. those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea were ...

the toxic impact of copper sulfate in lethal and sublethal concentrations was investigated on gill of grass carp, ctenopharynogodon idella . in this investigation, 27 specimens were used as control group and three treatment groups were treated with 2.5 and 5mg/l of copper sulfate. gill samples were collected from each treatment after 96hr and lesions were analyzed by light microscopy. in histop...