نتایج جستجو برای: epithelial cells of choroid plexus

تعداد نتایج: 21318226  

Journal: :Toxicology and applied pharmacology 2009
Mamta Behl Yanshu Zhang Andrew D Monnot Wendy Jiang Wei Zheng

The choroid plexus, a barrier between the blood and cerebrospinal fluid (CSF), is known to accumulate lead (Pb) and also possibly function to maintain brain's homeostasis of Abeta, an important peptide in the etiology of Alzheimer's disease. This study was designed to investigate if Pb exposure altered Abeta levels at the blood-CSF barrier in the choroid plexus. Rats received ip injection of 27...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2014
Robin K Young Alice R A Villalobos

The choroid plexus epithelium forms the blood-cerebrospinal fluid barrier and accumulates essential minerals and heavy metals. Choroid plexus is cited as being a "sink" for heavy metals and excess minerals, serving to minimize accumulation of these potentially toxic agents in the brain. An understanding of how low doses of contaminant metals might alter transport of other solutes in the choroid...

2012
Masaki Ueno Toshitaka Nakagawa Haruhiko Sakamoto

The mammalian brain restricts the entrance of ions and solutes circulating in the bloodstream by two cellular barriers, namely, the blood-brain barrier (BBB) and bloodcerebrospinal fluid (CSF) barrier (Brightman et al., 1970; Ballabh, 2004). The BBB is built up by a monolayer of endothelial cells (ECs) lining the brain capillaries that restricts the movement of small polar molecules and macromo...

Journal: :Archivum histologicum Japonicum = Nihon soshikigaku kiroku 1973
Y Hosoya T Fujita

The choroid plexus and the third ventricle wall of the rat brain were observed by scanning electron microscopy. Macrophages of various shapes known as Kolmer cells were attached to the ependymal surface of the choroid plexus densely covered with microvilli. Some cells possessed numerous fine processes radiating from the centrally located cell body and ending, often with an attenuated web-like t...

Journal: :PLoS ONE 2008
Brent R. Bill Darius Balciunas Joshua A. McCarra Eric D. Young Toua Xiong Ashley M. Spahn Marta Garcia-Lecea Vladimir Korzh Stephen C. Ekker Lisa A. Schimmenti

BACKGROUND The choroid plexus (CP) is an epithelial and vascular structure in the ventricular system of the brain that is a critical part of the blood-brain barrier. The CP has two primary functions, 1) to produce and regulate components of the cerebral spinal fluid, and 2) to inhibit entry into the brain of exogenous substances. Despite its importance in neurobiology, little is known about how...

2016
Ryotaro Suzuki Masaya Nagaishi Yoshiko Fujii Yoshihiro Tanaka Kensuke Suzuki Sumihito Nobusawa Hideaki Yokoo Akio Hyodo

Choroid plexus cysts (CPCs) are the most common neuroepithelial cysts, but rarely present with neurological signs or symptoms. Intracranial lipomas are generally seen at an interhemispheric location, and solitary choroid plexus lipomas (CPLs) have been reported in only a few cases. Here we report a symptomatic case of a 39-year-old woman with combined CPC and CPL on the lateral ventricle. She p...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1989
J A Nathanson L L Chun

Because the brain lacks a true lymphatic system, it is unclear how peripheral lymphocytes recognize foreign antigens present in the central nervous system. This report demonstrates that the choroid plexus, which constitutes the blood-cerebrospinal fluid barrier, is able to present foreign antigen to, and stimulate the proliferation of, peripheral helper T lymphocytes through an Ia-dependent, ma...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید